Recapitulation of Extracellular LAMININ Environment Maintains Stemness of Satellite Cells In  Vitro

In this study, examination of the satellite cell microenvironment in vivo revealed that these cells are encapsulated by LMα2–5. We find that reconstitution of the satellite cell niche with recombinant LM-E8 fragments promotes the proliferation and maintains satellite cells in an undifferentiated state.
Source: Stem Cell Reports - Category: Stem Cells Source Type: research