Transplantation or rurality? Migration and HIV risk among Chinese men who have sex with men in the urban areas.

CONCLUSIONS: The widely used local/migrant categorization obscures important differences in HIV risk present between urban/rural subgroups among them. Previous studies of HIV risks in Chinese "migrant" may have failed to consider the role of structural factors such as discrimination or barriers to healthcare when interpreting their findings of higher HIV prevalence in this population. Low ART uptake among rural transplant MSM in this study is particularly concerning and underscore the need for HIV-related interventions tailored for this group. PMID: 29327442 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

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is AD Abstract Cryptosporidium is a genus of single celled parasites capable of infecting a wide range of animals including humans. Cryptosporidium species are members of the phylum apicomplexa, which includes well-known genera such as Plasmodium and Toxoplasma. Cryptosporidium parasites cause a severe gastro-intestinal disease known as cryptosporidiosis. They are one of the most common causes of childhood diarrhoea worldwide, and infection can have prolonged detrimental effects on the development of children, but also can be life threatening to HIV/AIDS patients and transplant recipients. A variety of hosts can a...
Source: Experimental Parasitology - Category: Parasitology Authors: Tags: Exp Parasitol Source Type: research
[The Conversation Africa] A lifesaving partial liver transplant from an HIV-infected mother to her uninfected child - the first of its kind - was conducted last year at the University of the Witwatersrand's Donald Gordon Medical Centre in Johannesburg. More than a year later, both mother and child are doing well.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer's disease. I believe we're getting close to testing this therapy in people." Although earlier research established that antibodies significantly reduce amyloid buildup in the brain, researchers needed to find a safe way to introduce them into the body. A vaccine developed elsewhere showed promise in the early 2000s, but when tested in humans, it caused brain swelling in some patients. The new idea was to start with DNA codin...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: We report that partially matched T cells targeting PyVs generated from healthy related donors can be safely used for adoptive immunotherapy of severely immunocompromised patients with PML. Multiple infusions of T cells are very well tolerated at the doses of up to 2x10e6 PyVST cells/kg, displaying excellent safety profile without adverse events. Furthermore, our data suggest possible efficacy of this strategy as a life-saving therapy for patients who otherwise face a dismal prognosis.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 703. Adoptive Immunotherapy: Poster III Source Type: research
Background: The correct management of immunosuppressed patients with pneumonia is debated. We evaluate prevalence, risk factors and characteristics of immunosuppressed patients coming from the community with pneumoniaMethods: A secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia hospitalized in 222 hospitals in 54 countries worldwide was conducted. Risk factors for immunosuppression included: AIDS, aplastic anemia, asplenia, hematological malignancy, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroids use and solid tu...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Achieving the Sustainable Development Goal 3: challenges in HIV testing in the Eastern Mediterranean Region (Editorial). East Mediterr Health J. 2017 Dec 14;23(10):647-648 Authors: Hermez J, Khattabi H, Sabry A, Riedner G, Hajjeh R Abstract In the era prior to antiretroviral therapy (ART), taking an HIV test was associated with great fear, as a diagnosis of HIV infection signaled imminent death. As we mark World AIDS Day on 1 December 2017, it is worth reflecting on the success over the last two decades whereby treatment for HIV infection has become safer, more effective and simpler as new regimens w...
Source: Eastern Mediterranean Health Journal - Category: Middle East Health Tags: East Mediterr Health J Source Type: research
AbstractHumanized mice have become useful animal models for HIV/AIDS. Since NOD.Cg-Prkdc scid Il2rgtm1Wjl/SzJ (NSG) mice allow the engraftment of primary human immune cells, we aim to determine the role of human Fms-related tyrosine kinase 3 ligand (hFlt3L), a major growth factor for dendritic cells (DCs), in regulating the differentiation of cord blood-derived CD34+ progenitor cells in this murine species. Soluble recombinant hFlt3L protein and AAV-vectored hFlt3L were administrated before or after human CD34+ progenitor cell transplantation, respectively. We then measured the peripheral levels of hFlt3L by ELISA. Meantim...
Source: Journal of NeuroImmune Pharmacology - Category: Drugs & Pharmacology Source Type: research
Several factors underlie a profound reduction in the HIV-1 reservoir in patients who undergo allogeneic hematopoietic stem cell transplant (allo-HSCT) for hematologic disease, researchers report.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: HIV/AIDS News Source Type: news
Consortium Abstract Background: The multifactorial mechanisms associated with radical reductions in HIV-1 reservoirs after allogeneic hematopoietic stem cell transplant (allo-HSCT), including a case of HIV cure, are not fully understood. Objective: To investigate the mechanism of HIV-1 eradication associated with allo-HSCT. Design: Nested case series within the IciStem observational cohort. Setting: Multicenter European study. Participants: 6 HIV-infected, antiretroviral-treated participants who survived more than 2 years after allo-HSCT with CCR5 wild-type donor cells. Measurements: HIV ...
Source: Annals of Internal Medicine - Category: Internal Medicine Authors: Tags: Ann Intern Med Source Type: research
[Bhekisisa] This HIV-positive mother asked doctors to allow her to save her child. Read how she made history.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
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