Modular bicompartmental knee arthroplasty : Indications, technique, prosthetic design, and results.
Modular bicompartmental knee arthroplasty : Indications, technique, prosthetic design, and results. Acta Orthop Belg. 2017 Mar;83(1):124-131 Authors: Kanna R Abstract The shifting demographics of patients with localized knee arthritis, including younger, more active patients, is a chief motivation for mounting interest in tissue preserving surgical substitutes for total knee arthroplasty (TKA). Unlinked, modular bi-compartmental knee arthroplasty (MBKA) is an emerging knee-resurfacing approach that provides a conservative alternative to TKA. Arthritis involving both patellofemoral and either medial or lateral tibiofemoral compartments, with no significant deformity or bone deficiency, preserved motion, and intact cruciate ligaments, can be effectively managed with MBKA. It is tailored to treat the pathologic areas of knees with bicompartmental arthritis with the benefit of improved function and tissue conservation. MBKA done in appropriate patients, using precise technique, with appropriate implants has shown to give good short and long term functional results. Long term results using modern MBKA implants are awaited and may further establish the durability and success of the procedure. PMID: 29322904 [PubMed - in process]
Authors: Gwon SY, Rhee KJ, Sung HJ Abstract The risk of rheumatoid arthritis (RA), an autoimmune disease, in the elderly population increases along with that of atherosclerosis, cardiovascular disease, type 2 diabetes, and Alzheimer's disease. Identifying specific biomarkers for RA can clarify the underlying molecular mechanisms and can aid diagnosis and patient care. To this end, the present study investigated the genes and proteins that are differentially expressed in RA using a mouse collagen-induced arthritis (CIA) model. We performed gene microarray and proteome array analyses using blood samples from the mice...
We report a case series of multi-failure 16 patients, successfully treated with secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin-17A, recently approved for the treatment of plaque psoriasis, psoriatic arthritis and ankylosing spondylitis. PMID: 29334270 [PubMed - as supplied by publisher]
CONCLUSION: Pediatric uveitis is challenging to diagnose and manage, with frequent and potentially severe complications. Most cases were bilateral, recurrent, and idiopathic. Prompt referral to uveitis-specialized centers and an appropriate systemic therapy are mandatory for good visual outcomes. PMID: 29333911 [PubMed - as supplied by publisher]
Follow me on Twitter @DrClaire Sore throats happen all the time in childhood — and most of the time, it’s nothing to worry about. Most of the time, they are simply part of a common cold, don’t cause any problems, and get better without any treatment. Sometimes, though, a sore throat can be a sign of a problem that might need medical treatment. Here are four examples: Strep throat. This infection, caused by a particular kind of streptococcus bacteria, is quite common. Along with a sore throat, children may have a fever, headache, stomachache (sometimes with vomiting), and a fine, pink rash that almost look...
A team from Germany's Friedrich-Alexander-Universit ät Erlangen-Nürnberg recommend eating one breakfast food daily to reduce symptoms in rheumatoid arthritis.
Authors: Ivanova R, Goremykina M, Glushkova N, Vento S PMID: 29333800 [PubMed - in process]
Javier Rodr íguez-Carrio, Mercedes Alperi-López, Patricia López, Francisco J. Ballina-García, Ana Suárez
What do we currently know about the efficacy and safety of these biologic agents in the treatment of systemic onset juvenile idiopathic arthritis?Arthritis Research &Therapy
(Washington University School of Medicine) More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur after West Nile virus infects the brain. Now, a new study in mice suggests that such ongoing neurological deficits may be due to unresolved inflammation that hinders the brain's ability to repair damaged neurons and grow new ones. When the inflammation was reduced by treatment with an arthritis drug, the animals' ability to learn and remember remained sharp after West Nile disease.
(Kaunas University of Technology) ViLim Ball technology created at a Lithuanian startup company Fidens helps to reduce uncontrollable shaking hands, which is one of the symptoms of essential tremor. The technology is effective in 7 out of 10 cases, and it can also be used to alleviate morning stiffness of joints for rheumatoid arthritis sufferers.