Tocotrienol supplementation suppressed bone resorption and oxidative stress in postmenopausal osteopenic women: a 12-week randomized double-blinded placebo-controlled trial

ConclusionsTwelve-week annatto-extracted TT supplementation decreased bone resorption and improved bone turnover rate via suppressing bone remodeling regulators in postmenopausal women with osteopenia. Such osteoprotective TT ’s effects may be, in part, mediated by an inhibition of oxidative stress.Trial registrationClinicalTrials.gov identifier: NCT02058420. Title: Tocotrienols and bone health of postmenopausal women.

http://link.springer.com/10.1007/s00198-017-4356-x

Source: Osteoporosis International - January 12, 2018 Category: Orthopaedics Source Type: research