Log in to search using one of your social media accounts:

 

Escalating Symptoms of Anxiety May Point to Older Patients at Greatest Risk of Alzheimer ’s

Older adults experiencing worsening anxiety may have higher levels of a protein fragment implicated in Alzheimer ’s disease, according to astudy published today inAJP in Advance.Past studies have suggested depression and other neuropsychiatric symptoms may be predictors of Alzheimer ’s progression during its “preclinical” phase—a period marked by the accumulation of brain deposits of fibrillar amyloid and pathological tau in a patient’s brain. In the current study, Nancy J. Donovan, M.D., of Brigham and Women ’s Hospital and colleagues examined the association between brain amyloid beta and depression symptoms over time in cognitively normal, older adults.A total of 270 participants aged 62 to 90 underwent baseline positron emission tomography (PET) scans to measure cortical aggregate amyloid beta and annual depression assessments with the 30-item Geriatric Depression Scale (GDS). The team calculated total GDS scores as well as scores for three GDS item clusters: apathy-anhedonia, dysphoria, and anxiety-concentration. These scores were examined over a span of five years.“Rather than just looking at depression as a total score, we looked at specific symptoms such as anxiety,” Donovan said in apress release. “When compared to other symptoms of depression such as sadness or loss of interest, anxiety symptoms increased over time in those with higher amyloid beta levels in the brain.”“These results sugges...
Source: Psychiatr News - Category: Psychiatry Tags: Alzheimer's disease amyloid beta anxiety depression mild cognitive impairment Nancy Donovan Source Type: research

Related Links:

Background/ObjectivesBehavioral problems in individuals with Alzheimer's disease (AD) impose major management challenges. Current prevention strategies are anchored to cognitive outcomes, but behavioral outcomes may provide another, clinically relevant opportunity for preemptive therapy. We sought to determine whether personality changes that predispose to behavioral disorders arise during the transition from preclinical AD to mild cognitive impairment (MCI). DesignLongitudinal observational cohort study. SettingAcademic medical center. ParticipantsMembers of an apolipoprotein E (APOE) ɛ4 genetically enriched cohort of Ma...
Source: Journal of the American Geriatrics Society - Category: Geriatrics Authors: Tags: Clinical Investigation Source Type: research
The sign comes 10 years before memory and thinking problems are obvious. *** ~ THE EBOOKS ~ Escape from low mood or depression with my "Activate ebook" Discover how to deal with anxiety in my "Anxiety plan ebook" Boost your motivation for anything with my "Spark ebook" by Dr JEREMY DEAN ***
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
The drug protected nerve cell functioning, reduced inflammation and nerve cell loss. *** ~ THE EBOOKS ~ Escape from low mood or depression with my "Activate ebook" Discover how to deal with anxiety in my "Anxiety plan ebook" Boost your motivation for anything with my "Spark ebook" by Dr JEREMY DEAN ***
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
Alzheimer's linked to condition that affects 1 in 5 people in the US. *** ~ THE EBOOKS ~ Escape from low mood or depression with my "Activate ebook" Discover how to deal with anxiety in my "Anxiety plan ebook" Boost your motivation for anything with my "Spark ebook" by Dr JEREMY DEAN ***
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
This study provides additional evidence that Aβ administration can induce depression- and anxiety-like symptoms in rodents, and suggests that KATP channel inhibitors may be a plausible therapeutic strategy for treating affective disorders in AD patients. PMID: 29307659 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - Category: Neurology Authors: Tags: Brain Res Bull Source Type: research
The purpose of this study was to investigate the effect of an 8-week nursing intervention consisting of 2 weekly sessions of music and reminiscence therapy together with the application of reality orientation techniques. Our expectation at the onset of the study was that listening to music that was familiar and connected with the memory of past events would, due to the music's emotional impact, stimulate memory associations, leading, in turn, to a positive effect on depression and anxiety in people living with dementia. We carried out a pre-/posttest intervention design with a sample of 19 patients divided into 2 groups&md...
Source: Holistic Nursing Practice - Category: Nursing Tags: Features Source Type: research
The oil was linked to poor learning and weight gain. *** ~ THE EBOOKS ~ Escape from low mood or depression with my "Activate ebook" Discover how to deal with anxiety in my "Anxiety plan ebook" Boost your motivation for anything with my "Spark ebook" by Dr JEREMY DEAN ***
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Dementia Source Type: blogs
Imagine a world in which caring for the deeply forgetful is deemed a privilege and a trust.By Stephen PostAlzheimer's Reading RoomI do believe that we will see a spiritual-cultural shift away from the ideology of “hyper-cognitive values” that has regrettably blinded us to the enduring selves underlying the deeply forgetful.How can we encounter the deeply forgetful outside of hyper-cognitive ideologies?Dementia Patients are People TooHow can we bear witness to the reality that persons with this cognitive disability possess inherent qualities, and create a culture where all are welcomed and celebrated regardless ...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alz alzheimers bond cruelty deeply forgetful dehumanizing others demenitia glass half full love privilege self identity Spiritual Cultural Evolution Stephen Post trust Source Type: blogs
Introduction: Patients with Alzheimer's Disease, besides cognitive problems, can also show many behavioral and psychological problems, which are known as BPSD (Behavioral and Psychological Symptom of Dementia). BPSD consists of sleep wake rhythm disorders, hallucinations, depressive mood, anxiety, odd behavior like wandering, restlessness, agitation, sexual disinhibition and cursing. Some studies highlighted that about 64% of patients with Alzheimer's presents with at leas tone of those symptoms at their first clinical evaluation.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Behavior, Cognition and Dreaming Source Type: research
One of the most important things I learned as an Alzheimer's caregiver was how to use bright light to change my mother's mood and behavior.By Bob DeMarcoAlzheimer's Reading RoomMy mother, Dotty, had a tendency to get in a bad mood around 4:30 PM each day. It was like a form of sundowning. Learn more about that situation by following this link.Twilight Moments in Dementia Patients - Sundowning SyndromeShe might say things like I'm going to bed,or something much worse.What really struck me was the look on her face. It seemed like she wasn't there; or, sometimes like she as very unhappy. I didn't like the look on her face and...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: Alzheimers Dementia alzheimers reading room bright light bright light alzheimers care of dementia patients how to learning Source Type: blogs
More News: Alzheimer's | Anxiety | Brain | Dementia | Depression | Geriatrics | Hospitals | Neurology | PET Scan | Psychiatry | Study | Women