Clinical management of a unique case of PNET of the uterus during pregnancy, and review of the literature

AbstractRationale:PNETs (primitive neuroectodermal tumors) are a family of highly malignant neoplasms characterized by small round cells of neuroepithelial origin. They usually involve bone and soft tissues, and have a higher incidence in childhood.Patient concerns:In this case report, we describe the obstetric and oncological outcome of a huge mass diagnosed as a leiomyoma in a 39-year-old pregnant woman who complained of low back pain, dysuria, and urinary frequency at 22 weeks of gestation.Diagnoses:During the 25th week of pregnancy, the patient was referred to our hospital at night with severe anemia and suspected hemoperitoneum. She underwent an emergency caesarean section, delivering a female fetus weighing 400 g, with an Apgar score of 7 at 1 minute and 9 at 5 minutes.Intervention:During surgery, we found a huge uterine sarcoma-like metastatic tumor, invading the pelvic peritoneum and parametria bilaterally; the adnexae seemed disease-free. We performed a type B radical hysterectomy, bilateral salpingo-oophorectomy, pelvic peritonectomy, omentectomy, appendectomy, and excision of a bulky lymph node. Seven days after delivery, staging computed tomography (CT) scan demonstrated a large lombo-aortic lymph node compressing the left renal vein and we completed debulking with a second surgery, including diaphragmatic peritonectomy and excision of a huge lymph node by lombo-aortic lymphadenectomy, requiring partial reconstruction of an infiltrated renal vein.Outcome:Ten...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

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(MedPage Today) -- But increase in risk of neonatal readmission, major malformations
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Authors: Iwakiri K, Sotoyama M, Takahashi M, Liu X, Koda S, Ichikawa K Abstract Many care workers at elderly care facilities in Japan suffer occupational low back pain (LBP) despite the utilization of welfare equipment. When introducing welfare equipment such as hoists and sliding boards, education on appropriate care methods using welfare equipment is usually conducted, but the effect of education diminishes with time. This intervention study aimed to examine the effect of re-education on appropriate care methods using welfare equipment on the prevention of care workers' LBP at an elderly care facility. At the int...
Source: Industrial Health - Category: Occupational Health Tags: Ind Health Source Type: research
Authors: Norum J, Balteskard L, Thomsen MW, Kvernmo HD Abstract Rough weather conditions in the subarctic areas of Norway may influence on the risk of wrist fracture. We implemented data from the Norwegian System of Patient Injury Compensation (NPE). All claims due to wrist surgery, performed at the public hospitals in Northern Norway, during 2005-2014 were analyzed. We employed the ICD-10 classification codes S52.5 (fracture of distal end of radius) and S52.6 (fracture of distal end of radius and ulna). Treatment was defined by NCSP codes. 84 patients (0.3%) complained. Females complained four times more often tha...
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
(Reuters Health) - Fathers' use of antidepressant medications around the time mothers become pregnant does not increase babies' risk of preterm birth, birth defects, autism or intellectual disability, according to a study in the BMJ.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
This study aims to explore what adolescents experience to be of importance and helpful for their well-being through their lives in lodgings during senior high school. Qualitative, in-depth interviews were performed among 21 adolescents from the ages of 16 to 18 of both genders living in lodgings in a Norwegian county. Eleven interviews were performed in 2008 and 10 interviews performed in 2016. Interviews were analysed using qualitative content analysis. Two main categories and six subcategories were identified as important for well-being: (1) Conditions for well-being, me and my surroundings: (a) practical support; (b) re...
Source: International Journal of Qualitative Studies on Health and Well-being - Category: International Medicine & Public Health Tags: Int J Qual Stud Health Well-being Source Type: research
CONCLUSIONS:   In participants reporting HxLBP, TrA thickness modulations were lower and both tabletop and seated thickness modulations were able to distinguish reported HxLBP status. These findings suggest that TrA muscle function may be altered by HxLBP. PMID: 29912568 [PubMed - as supplied by publisher]
Source: Journal of Athletic Training - Category: Sports Medicine Tags: J Athl Train Source Type: research
ConclusionsOnco-Move is not likely to be cost-effective. Depending on the decision-makers ’ willingness-to-pay, OnTrack could be considered cost-effective in comparison with UC.Trial registration Clinical trial registration number of the Netherlands Trial Register —NTR2159.
Source: The European Journal of Health Economics - Category: Health Management Source Type: research
VITAMIN B12 deficiency can result in anaemia, but among its symptoms are headaches and a reduced appetite. The vitamin is vital in keeping the body in the best condition, but because the body doesn ’t make the vitamin it’s important to get it from a balanced diet. Here are six foods that are all good sources of B12.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Essel KG, Moore KN Abstract INTRODUCTION: Niraparib, an orally available selective inhibitor of poly(adenosine diphosphate-ribose) polymerase (PARP) is the first PARP inhibitor approved for use in patients with ovarian cancer who do not harbor a germline or somatic mutation in the breast cancer gene (BRCA). Overall niraparib is well tolerated and its toxicities, primarily hematologic, are manageable especially with recently released initial dose modification guidelines based on weight and baseline platelet count. The role of niraparib as maintenance following front-line platinum-based chemotherapy as well ...
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
On page 5 of my Wall Street Journal this morning, and page 7 of my Washington Post, a full-page ad for Wells Fargo bannersWells Fargo and NextEra Energy join together to fuel  low-carbon economy throughout the U.S. Meanwhile, the front page of my JournalannouncesGreen-Power King Thrives on Government SubsidiesThe article explains that NextEra Energyhas grown into a green Goliath, almost entirely under the radar, not through taking on heavy debt to expand or by touting its greenness, but by relentlessly capitalizing on government support for renewable energy, in particular the tax subsidies that help finance  ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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