Drug users find safety, community in underground injection facility
(Reuters Health) - - Intravenous drug users who inject in a secret U.S. facility where staff provide clean needles and guard against overdoses say they appreciate the site for letting them in off the streets and for its history-shaping role.
Tom Petty's Cause of Death: Accidental Overdose
Drug deaths draw the most notice, but more addicted people live than die. For them and their families, life can be a relentless cycle of worry, hope and chaos.
Musician Tom Petty died of an accidental drug overdose, according to a statement from his wife and daughter that was posted online.Petty had been suffering from a fractured hip that got worse during his recent tour, along with emphysema and knee pain.
The wife and eldest daughter of Tom Petty announced this evening that the rock and roll legend died in October from an accidental overdose of opioids prescribed for a fractured hip and other chronic ailments. At the time, the cause of death of the 66-year-old Petty was listed as cardiac arrest.
See something of interest? Please share our postings with colleagues in your institutions! Spotlight All NNLM MAR funding opportunities are currently closed. In February, we will announce opportunities to apply for projects starting May 15, 2018. Now is the perfect time to start meeting with potential partners and consulting with NNLM MAR staff on health information outreach ideas. Contact us to set up a consultation. National Drug and Alcohol Facts Week® begins on Monday! If your organization is getting involved with busting myths about drug use or addiction, tell us about it! NNLM MAR is always interested in learning...
Initiative works to tackle some of the most pressing challenges to public health in the United States: Addiction and Overdose, Environmental Challenges, Obesity and the Food System, Risks to Adolescent Health and Violence.
(Beth Israel Deaconess Medical Center) With opioid overdoses now a leading cause of nonintentional death in the United States, data show most of these deaths can be traced back to an initial prescription opioid. A new study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS) sheds light on the possible link between physicians' opioid prescription patterns and subsequent abuse.
Keith Humphreys' Comment in The Lancet (July 29, 2017, p 437)1 describes the main drivers of the opioid crisis in the USA and advocates for global restriction of prescription opioids as an effective public health response to addressing the overdose epidemic. We argue that although the dominant narrative about the opioid crisis circulating around careless prescribing and unscrupulous pharmaceutical companies has some merit, it does not tell the whole story of the epidemic of opioid addiction in North America because it occurs among medical and non-medical opioid users.
I agree with Mohammad Karamouzian and Thomas Kerr that “restricting access to prescription opioids for opioid-naive populations should be included in the primary strategies” in response to the epidemic of opioid overdose and addiction, as discussed in my Comment.1 Karamouzian and Kerr are also correct to note that people currently taking opioids wil l require different clinical and policy strategies. For example, some people with chronic pain conditions will need to remain on their medication indefinitely because the net costs and benefits of doing so are favourable.
Publication date: Available online 10 January 2018 Source:Chemico-Biological Interactions Author(s): Zhenyu Shen, Yu Wang, Zhenhui Su, Ruirui Kou, Keqin Xie, Fuyong Song Acetaminophen (APAP) overdose can cause severe liver failure even death. Nearly half of drug-induced liver injury is attributed to APAP in the US and many European countries. Oxidative stress has been validated as a critical event involved in APAP-induced liver failure. p62/SQSTM1, a selective autophagy adaptor protein, is reported to regulate Nrf2-ARE antioxidant pathway in response to oxidative stress. However, the exact role of p62-keap1-Nrf2 antioxida...