Levothyroxine may improve fertility in Hashimoto ’s patients

For women with infertility and Hashimoto’s thyroiditis, levothyroxine treatment can improve ovarian function, according to a study published inThe Journal of Obstetrics and Gynaecology Research.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Abstract Thyroid hormones are vital for the proper functioning of the female reproductive system, since they modulate the metabolism and development of ovarian, uterine and placental tissues. Therefore, hypo- and hyperthyroidism may result in subfertility or infertility in both women and animals. Other well-documented sequelae of maternal thyroid dysfunctions include menstrual/estral irregularity, anovulation, abortion, preterm delivery, preeclampsia, intrauterine growth restriction, postpartum thyroiditis, and mental retardation in children. Several studies have been carried out involving prospective and retrospe...
Source: Biology of Reproduction - Category: Reproduction Medicine Authors: Tags: Biol Reprod Source Type: research
Journal of Obstetrics and Gynaecology Research, EarlyView.
Source: Journal of Obstetrics and Gynaecology Research - Category: OBGYN Source Type: research
AbstractRationale:Thyrotropin-secreting adenoma (TSHoma) is rare, diagnosis and treatment are often delayed if the condition coexists with Hashimoto thyroiditis. The enlarged pituitary adenoma may eventually induce panhypopituitarism, infertility, or the compression of optic nerves and optic chiasma.Patient concerns:This patient was a 36-year-old man who had been referred to the pituitary disease multidisciplinary team (MDT) of the West China Hospital, due to infertility.Diagnoses:Examinations revealed pituitary thyrotropin-secreting macroadenoma.Interventions:We conducted trans-sphenoidal surgery. Human chorionic gonadotr...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: Available online 12 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Simone De Leo, Elizabeth N Pearce Understanding of changes in thyroid function and the consequences of thyroid disease during pregnancy has rapidly grown in the past two decades, and revised American Thyroid Association guidelines on this topic were published in 2017. This Review explores the association between thyroid autoimmunity and complications during and after pregnancy. Thyroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyroid-stimulating hormone receptor ant...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
We examined the most common immune disorders, which were identified by ICD9 diagnosis codes. Men diagnosed with an immune disorder at baseline or within 1 year of follow‐up were excluded. Infertile men were compared to vasectomized men (i.e., men who are likely fertile) and to age‐matched control (10 : 1) group using Cox regression analysis. A total of 33,077 infertile men (mean age of 33 years), 77,693 vasectomized men (mean age 35), and 330,770 age‐matched control men (mean age 33) were assembled with a total follow‐up of 1.49 M person‐years. Overall, immune disorders were rare in the g...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
Conditions:   Infertility;   Autoimmune Thyroiditis Interventions:   Drug: Immunomodulatory;   Drug: Thyroxine Sponsor:   Aljazeera Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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