Both Serum Brain-Derived Neurotrophic Factor and Interleukin-6 Levels Are Not Associated with Therapeutic Response to Lamotrigine Augmentation Therapy in Treatment-Resistant Depressive Disorder

Conclusion: The present study suggests that the acute effect of lamotrigine augmentation therapy for a major depressive episode is not related to either BDNF or IL-6, at least in patients with treatment-resistant depressive disorder.Neuropsychobiology 2017;75:145 –150
Source: Neuropsychobiology - Category: Psychiatry & Psychology Source Type: research

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Most patients with bipolar disorder have depressive onset polarity. There is, however, very few studies investigating predictors of hypomanic and/or manic change for patients with major depression in Japan.1 We preliminary explored predictors of...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
We describe a 35-year-old woman who died due to lack of recognition of SIADH. The patient, who had a bipolar disorder and was for a long time on a paliperidone depot, developed complaints of nausea, vomiting and thirst after lamotrigine was prescribed. A few days after increasing the dose, she died; no evidence was found of suicide. The SIADH was probably triggered by the use of lamotrigine and paliperidone. Paying sufficient attention to the symptoms that may cause this syndrome, as well as their early recognition, could save lives. PMID: 30536299 [PubMed - in process]
Source: Tijdschrift voor Psychiatrie - Category: Psychiatry Authors: Tags: Tijdschr Psychiatr Source Type: research
Among offspring of individuals with bipolar disorder, 25% were diagnosed with the disorder, according to astudy published in AJP in Advance. The study found that childhood sleep and anxiety disorders may be important predictors of the illness.Participants with childhood anxiety disorders or sleep disorders were nearly twice as likely to develop mood disorder, according to Anne Duffy, M.D., a professor in the Department of Psychiatry at Queen ’s University in Canada, and colleagues. Children with depressive or manic symptoms were 2.7 times more likely and 2.3 times more likely, respectively, to develop mood disorder.T...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance Anne Duffy anxiety bipolar disorder children manic symptoms predictors sleep disorders Source Type: research
Authors: Pandya SP Abstract There is a need to generate evidence on whether meditationęž‹s core aspect of building and nurturing calm and peace serves as a mood stabilizer for current and recurrent episodes of depression through the acute and maintenance phases of treating bipolar disorder II affected patients. A two-year longitudinal multi-city randomized controlled trial experiment was conducted comprising 311 bipolar disorder II affected patients in the intervention and control group respectively across eight African and Asian cities. The Bipolar Depression Rating Scale (BDRS) was administered with the intervent...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
 Living in our fast-paced world, many of us find ourselves stressed out, and many others don’t even realize how stressed they’ve become. Many people choose to ignore their stress, others use meditation, exercise, or other endeavors to reduce stress. This episode shares the story of a woman whose solution to stress involves regularly making challah, a traditional Jewish bread. Not only does the ritual of the making of the bread reduce stress, but the history and tradition of the bread are also important to her. Subscribe to Our Show! And Remember to Review Us! About Our Guest Beth Ricanat...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mindfulness Stress The Psych Central Show Beth Ricanati challah Gabe Howard Vincent M. Wales Source Type: blogs
(American College of Neuropsychopharmacology) About 3 million people in the US are diagnosed every year with bipolar disorder, a psychiatric condition characterized by dramatic shifts in mood from depression to mania. Currently, the standard treatment includes a combination of psychotherapy and prescription medications such as mood stabilizers and antipsychotics.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
You're reading A Wee Wiggle in my Journey to Family, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Many of us have faced depression, struggled with low self-esteem, and other debilitating mental health challenges. My own journey with depression was a result of growing up with a rare blood disorder and being told I could never have children of my own. This completely changed my dreams of what family and life meant. Years later I suffered with a rare soft tissue sarcoma, yet, baffling the best of doctors, I survived. I&rs...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: depression featured psychology self improvement best books Donna Grant Wilcox faith family mental health pickthebrain Source Type: blogs
Authors: Desbeaumes Jodoin V, Miron JP, Lespérance P Abstract OBJECTIVE: Major depressive disorder (MDD) is a prevalent condition in older adults. Although antidepressant drugs are commonly prescribed, efficacy is variable, and older patients are more prone to side effects. Repetitive transcranial magnetic stimulation (rTMS) is an alternative therapy used increasingly in the treatment of MDD. Even though recent studies have shown efficacy of rTMS in elderly depressed patients, the safety and efficacy of accelerated rTMS has not been studied in this population. METHODS: Data were retrospectively analyzed ...
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
This case-control study examines the real-time changes and associations between physical activity, sleep patterns, and energy and mood levels in people with and those without bipolar or depressive disorder.
Source: JAMA Psychiatry - Category: Psychiatry Source Type: research
CONCLUSIONS:: Bipolar disorder in individuals at familial risk typically unfolds in a progressive clinical sequence. Childhood sleep and anxiety disorders are important predictors, as are clinically significant mood symptoms and psychotic symptoms in depressive episodes. PMID: 30525908 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
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