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'UK should follow Wales' lead on organ donation'

Liver transplant patient Ellie Lacey urges other UK nations to move to presumed consent organ donation.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news

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This article provides recommendations for the diagnosis and management of cardiac and pulmonary vascular disease in liver transplant candidates.American Journal of Transplantation
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Transplantation Journal Article Source Type: news
This study aimed to report outcomes of liver–kidney transplantation in a coho rt of pediatric patients.MethodsWe retrospectively analyzed all pediatric liver –kidney transplantations performed in our center between September 2000 and August 2015. Patient data were obtained by reviewing inpatient and outpatient medical records and our transplant database.ResultsA total of 14 liver –kidney transplants were performed during the study period, with a median patient age and weight at transplant of 144.4 months (131.0–147.7) and 27.3 kg (12.0–45.1), respectively. The indications for liver&n...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
ConclusionsMass-forming extramedullary hematopoiesis is rare; however, our report emphasizes that it needs to be considered in the initial differential diagnosis of hepatic lesions arising in the setting of bone marrow disorders. We also show that in the setting of diffuse hepatic iron overload, tumefactive extramedullary hematopoiesis appeared isointense to background liver on T2* gradient-echo sequence, while adenoma, hepatoma, and hepatic metastasis appear hyperintense. Thus, T2*-weighted gradient-echo sequence may have a potential role in the imaging diagnosis of mass-forming hepatic extramedullary hematopoiesis arisin...
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Using liver elastography to diagnose sinusoidal obstruction syndrome in pediatric patients undergoing hematopoetic stem cell transplant, Published online: 15 January 2018; doi:10.1038/s41409-017-0064-6Using liver elastography to diagnose sinusoidal obstruction syndrome in pediatric patients undergoing hematopoetic stem cell transplant
Source: Bone Marrow Transplantation - Category: Hematology Authors: Source Type: research
Authors: Lin R, Wang Y, Ji K, Liu Z, Xiao S, Zhou D, Chen Q, Shi B Abstract Due to the lack of potential organs, hepatocellular transplantation has been considered for treating end-stage liver disease. Induced pluripotent stem cells (iPSCs) are reverted from somatic cells and are able to differentiate into hepatocytes. The present study aimed to investigate the mechanisms underlying iPSC differentiation to hepatocytes. GSE66076 was downloaded from the Gene Expression Omnibus; this database includes data from 3 undifferentiated (T0), 3 definitive endoderm (T5), and 3 early hepatocyte (T24) samples across hepatic‑d...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
CONCLUSION: The results of this meta-analysis showed that elevated pretransplant NLR may be used as a new prognostic predictor after LT for HCC. PMID: 29327595 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
CONCLUSIONS: Our work summarises current knowledge regarding clinical presentation, disease course, and prognosis of TCM-ILI. TCM can result in hepatotoxicity, even death or necessitate life-saving liver transplantation. Governmental regulation of TCM products should be strictly established. PMID: 29323538 [PubMed - as supplied by publisher]
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Authors: Shahab O, Golabi P, Younossi ZM Abstract Hepatitis C virus (HCV) infection affects many organs in the body, including the liver, kidneys, skin, joints and others. Although the hepatic manifestation of HCV has been widely studied, the extrahepatic manifestaions of HCV have not been fully appreciated. Studies have shown that patients with HCV have a higher risk of chronic kidney disease and end-stage renal disease, as well as poorer outcomes after kidney transplantation. Given these findings, it is important to screen HCV patients for presence of renal impairement in a timely manner. Current guidelines recom...
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
We examined the clinical and biochemical features of 19 patients with HBV-ALF who were treated in the early stage of the disease between 2000 and 2015. Results Fourteen patients received CS and NA (CS + NA group) and 5 received NA monotherapy (NA group). Eleven patients (58%) survived and 8 (42%) died. The survival rates in the CS + NA and NA groups were 64% and 40%, respectively (p=0.60). The mean ALT levels declined significantly at week 2 in both groups. The mean PT activities improved significantly at weeks 1 and 2 in the CS + NA group (p
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
A British surgeon who burned his initials onto patients' livers during transplant operations has been fined the equivalent of $17,100 Cdn and ordered to perform community service.
Source: CBC | Health - Category: Consumer Health News Tags: News/World Source Type: news
More News: Health | Liver | Liver Transplant | Transplant Surgery | Transplants | Urology & Nephrology | Wales Health