Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopmental disorders in offspring: A systematic review and meta ‐analysis

ConclusionMaternal hypothyroxinaemia and subclinical hypothyroidism may be associated with intellectual disability in offspring. Currently there is no evidence that levothyroxine treatment, when initiated 8 to 20 weeks gestation (mostly between 12‐17 weeks), for mild maternal thyroid hormone insufficiency during pregnancy reduces intellectual disability in offspring.This article is protected by copyright. All rights reserved.

Source: Clinical Endocrinology - January 1, 2018 Category: Endocrinology Authors: William Thompson, Ginny Russell, Genevieve Baragwanath, Justin Matthews, Bijay Vaidya, Jo Thompson ‐Coon Tags: Original Article Source Type: research