Relationship between obesity and iron deficiency anemia: is there a role of hepcidin?

Relationship between obesity and iron deficiency anemia: is there a role of hepcidin? Hematology. 2018 Jan 10;:1-7 Authors: Sal E, Yenicesu I, Celik N, Pasaoglu H, Celik B, Pasaoglu OT, Kaya Z, Kocak U, Camurdan O, Bideci A, Cinaz P Abstract OBJECTIVES: Iron deficiency is common in obese children although the underlying mechanism is unclear. The aim of this study was to investigate the associations between iron parameters, leptin, hepcidin and adiponectin levels in obese children. METHODS: A total of 237 children, ranging in age from 5 to 18 years, 180 with primary obesity and 57 healthy children and adolescents, were enrolled. Complete blood count, serum iron levels, iron-binding capacity, ferritin levels, leptin, hepcidin and adiponectin levels were studied. RESULTS: White blood cell and platelet count, iron-binding capacity, high-sensitive C-reactive protein, leptin and hepcidin values in the obese group were higher than those of the control group (p 
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research

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AbstractThe One Anastomosis (Mini) Gastric Bypass is rapidly gaining acceptance. This review reports cumulative results of 12,807 procedures in obese patients with a mean age of 41.18  years and BMI of 46.6 kg/m2. The overall mortality was 0.10% and the leak rate was 0.96%. The follow-up duration ranged from 6  months to 12 years. A marginal ulceration rate of 2.7% and an anaemia rate of 7.0% were reported. Approximately 2.0% of patients reported postoperative gastro-oesophageal reflux and 0.71% developed malnutrition. Excess weight loss at 6, 12, 24 and 60 months was 60.68, 72.56, 78.2 and 76.6% r...
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsLa prévalence élevée de la DE et la multiplicité des facteurs de risque sont une nouvelle illustration de la gravité de ce trouble sexuel chez les insuffisants rénaux chronique.AbstractObjectiveTo screen for erectile dysfunction in patients with chronic renal failure and to identify its risk factors.Patients and methodsA cross sectional study was carried out in 30 patients with chronic renal failure. Erectile dysfunction was assessed by using the International Index of Erectile Function (IIEF-5).ResultsPatients mean age was 49.6 ± 9 years. The average IIEF score w...
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
Publication date: July 2018Source: The Lancet Haematology, Volume 5, Issue 7Author(s): Juan Carlos Montano-Pedroso, Elvio Bueno Garcia, Mariana Alcântara Rodrigues de Moraes, Daniela Francescato Veiga, Lydia Masako FerreiraSummaryBackgroundAnaemia and iron deficiency are common after post-bariatric abdominoplasty, which can involve removal of large areas of skin with associated blood loss. Because the oral absorbability of iron is reduced after bariatric surgery (through reduced intake, reduction of gastric acid secretion for conjugation of iron, and separation of the iron-absorptive areas of the duodenum and jejunum...
Source: The Lancet Haematology - Category: Hematology Source Type: research
ConclusionsLa prévalence élevée de la DE et la multiplicité des facteurs de risque sont une nouvelle illustration de la gravité de ce trouble sexuel chez les insuffisants rénaux chronique.AbstractObjectiveTo screen for erectile dysfunction in patients with chronic renal failure and to identify its risk factors.Patients and methodsA cross sectional study was carried out in 30 patients with chronic renal failure. Erectile dysfunction was assessed by using the International Index of Erectile Function (IIEF-5).ResultsPatients mean age was 49.6 ± 9 years. The average IIEF score w...
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
Publication date: July 2018Source: The Lancet Haematology, Volume 5, Issue 7Author(s): Juan Carlos Montano-Pedroso, Elvio Bueno Garcia, Mariana Alcântara Rodrigues de Moraes, Daniela Francescato Veiga, Lydia Masako FerreiraSummaryBackgroundAnaemia and iron deficiency are common after post-bariatric abdominoplasty, which can involve removal of large areas of skin with associated blood loss. Because the oral absorbability of iron is reduced after bariatric surgery (through reduced intake, reduction of gastric acid secretion for conjugation of iron, and separation of the iron-absorptive areas of the duodenum and jejunum...
Source: The Lancet Haematology - Category: Hematology Source Type: research
This study aimed to characterize and identify determinants of anemia in this neonatal population. METHODS: Umbilical cord blood obtained from 183 neonates was utilized to assess hemoglobin (Hb), ferritin (SF), soluble transferrin receptor (sTfR), hepcidin, serum Fe, erythropoietin, folate, vitamin B-12, C-reactive protein, and interleukin-6. Associations with maternal Fe status were explored. RESULTS: Cord Hb or SF did not change significantly as a function of gestational age at birth (25-38 wks). Neonates born to women who were obese prior to pregnancy or smoked cigarettes during pregnancy had a 4-5-fold greater...
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research
Conclusion: The current study has given an insight into the microbiota of colorectal cancer patients in Saudi Arabia and has identified various genera significantly present in these patients when compared to those of the control group. PMID: 29887882 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Conclusion: Screening breast cancer patients for thyroid function status at baseline and serially post-treatment to evaluate the need for thyroid hormone replacement may provide for a novel strategy for treating chemotherapy-induced fatigue. PMID: 29876020 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
AbstractPurpose of ReviewPeriprosthetic joint infection (PJI) remains a complication that is associated with high morbidity as well as high healthcare expenses. The purpose of this review is to examine patient and perioperative modifiable risk factors that can be altered to help improve rates of PJI.Recent FindingsEvidence-based review of literature shows that improved control of post-operative glycemia, appropriate management of obesity, malnutrition, metabolic syndrome, preoperative anemia, and smoking cessation can help minimize risk of PJI. Additionally, use ofStaphylococcus aureus screening, preoperative evaluation of...
Source: Current Reviews in Musculoskeletal Medicine - Category: Orthopaedics Source Type: research
This study should make it possible to establish a predictive test, detect the ACS early, and consider a prophylactic decompression in the operating room. Trial registration: ClinicalTrials.gov, NCT02859662, Registered on 4 August 2016.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
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