Prevalence of Group B Streptococcus in Pregnant Women in Iran: A Systematic Review and Meta-analysis
Conclusions: The results of this study indicate that GBS screening measures and chemoprophylaxis guidelines concerning GBS infections must be established for pregnant women in Iran, and these guidelines must provide guidance for obstetricians, midwives and neonatologists on the prevention of GBS infections.
Authors: Vojtek I, Dieussaert I, Doherty TM, Franck V, Hanssens L, Miller J, Bekkat-Berkani R, Kandeil W, Prado-Cohrs D, Vyse A Abstract Pregnancy and the post-partum period are associated with elevated risks to both mother and infant from infectious disease. Vaccination of pregnant women, also called maternal immunization, has the potential to protect pregnant women, fetuses, and infants from several vaccine-preventable diseases. Maternal immunoglobulin G antibodies are actively transferred through the placenta to provide passive immunity to newborns during the first months of life, until the time for infant vacci...
Recently, lactobacilli-containing probiotics have been studied for use in a variety of conditions, including urogenital infections. We sought to determine if antenatal probiotic supplementation during second and third trimesters reduces maternal GBS rectovaginal colonization in pregnant women at 35-37 weeks ’ gestational age.
Microbial communities at different sites influence both health and disease. The cervicovaginal (CV) microbiota have documented associations with sexually transmitted infection acquisition and spontaneous preterm birth. While colonization with Group B Streptococcus (GBS) is prevalent, it remains a significant risk factor for neonatal morbidity. There are no data on how CV microbial communities might influence colonization with GBS. Therefore, the objective of this study was to determine if the CV microbiota is associated with GBS colonization (GBS-C) in pregnant women.
ConclusionPregnant women and healthcare professionals were open to the idea of an antenatal GBS vaccine and involvement in clinical trials of such a vaccine. Education and support from midwives would be key to successful implementation.This article is protected by copyright. All rights reserved.
Conclusions The protein peak of 6251 Da may play a role of emergence of ST-1 clone, serotype VI GBS in central Taiwan and could be useful in rapid identifying invasive serotype VI from III isolates, which is hardly achieved by LA.
CONCLUSIONS: The protein peak of 6251 Da may play a role of emergence of ST-1 clone, serotype VI GBS in central Taiwan and could be useful in rapid identifying invasive serotype VI from III isolates, which is hardly achieved by LA. PMID: 29317173 [PubMed - as supplied by publisher]
Authors: Saad EJ, Baenas DF, Boisseau CS, García MJ, Núñez SA, Sanchez PE, Balderramo DC, Hernández D, Caeiro JP Abstract Streptococcus agalactiae or group B streptococcus (GBS) is a frequent pathogen in immunocompromised adults. The aim of this study was to determine the relative frequency, clinical presentation, antimicrobial susceptibility profile, and risk factors associated with GBS bacteremia in non-pregnant adult patients. We conducted a retrospective analysis of blood cultures performed in two hospitals between the years 2009-2013. From 1110 bacteremia episodes, 13 were caused by...
To conduct a pilot study to determine the prevalence of GBS among pregnant women in Amman, Jordan, where Group B Streptococcus (GBS) testing is not routine.
Maternal GBS colonization is associated with early-onset neonatal sepsis and extensive efforts are directed to preventing this complication. Less is known regarding the maternal risks of GBS colonization. We seek to provide a modern estimate of the incidence of GBS colonization as well as invasive GBS disease.
Conclusions based on our transcriptomics data were further supported by responses of prostaglandin E2 (PGE2) and matrix metalloproteinases 1 (MMP1) and 3 (MMP3), all of which are known to be involved in parturition and premature rupture of membranes. These results support our initial hypothesis and provide new information on molecular targets of GBS infection in human extraplacental membranes. PMID: 29155939 [PubMed - as supplied by publisher]