Dengue takes low and slow approach to replication

(Duke University) Dengue virus slowly takes over the endoplasmic reticulum, the production site for a subset of host proteins, and steers clear of the cytosol, the fluid-filled space where the majority of host cellular proteins are synthesized. Its viral RNA template is translated into protein in such an inefficient, lackadaisical manner that it doesn't trip alarms.

Source: EurekAlert! - Infectious and Emerging Diseases - January 11, 2018 Category: Infectious Diseases Source Type: news