Algorithm Picks Relevant Variables Variables help predict survivability with myelodysplastic syndromes

Aziz Nazha, MD from the Cleveland Clinic discusses algorithm picks relevant variables and variables help predict survivability with myelodysplastic syndromes at the 2017 American Society of Hematology... Author: ASHReport Added: 01/11/2018
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts

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Conditions:   Acute Myeloid Leukemia;   Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome;   Cancer Fatigue;   Secondary Acute Myeloid Leukemia Interventions:   Behavioral: Cognitive Behavior Therapy;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia Interventions:   Drug: abaloparatide;   Drug: bevacizumab Sponsor:   University of Rochester Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   MDS Interventions:   Drug: APR-246 + azacitidine;   Drug: Azacitidine Sponsor:   Aprea Therapeutics AB Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   MDS Interventions:   Drug: APR-246 + azacitidine;   Drug: Azacitidine Sponsor:   Aprea Therapeutics AB Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia Interventions:   Drug: abaloparatide;   Drug: bevacizumab Sponsor:   University of Rochester Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   MDS Interventions:   Drug: APR-246 + azacitidine;   Drug: Azacitidine Sponsor:   Aprea Therapeutics AB Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Kim HY, Cho EJ, Chun S, Kim KH, Cho D Abstract Red blood cell (RBC) alloimmunization varies across human populations and ethnic groups. We evaluated the characteristics of RBC alloimmunization and compared the risk of alloimmunization in Korean patients with myelodysplastic syndrome (MDS) and liver cirrhosis (LC), two representative diseases in which chronic transfusion is required. In total, 115 MDS patients and 202 LC patients transfused with RBCs between 2013 and 2015 were retrospectively included. Twenty patients (6.3%) were newly alloimmunized (five MDS patients, 4.3%; 15 LC patients, 7.4%). The media...
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research
CONCLUSIONS: HS-FCM can sensitively detect minor PNH clones and reduce false-positive C-FCM minor PNH clone cases in AA/low-grade MDS patients. PMID: 30430777 [PubMed - in process]
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research
Conditions:   Myelodysplastic Syndromes;   Leukemia Acute Myeloid Intervention:   Drug: AG-221 Sponsor:   Groupe Francophone des Myelodysplasies Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this study, we introduce an easy-to-use and cross-laboratory, standardized two-dimensional migration assay for neutrophil granulocytes from peripheral blood. By combining time-lapse video microscopy and automated cell tracking, we calculated the average migration of neutrophils from 111 individual participants of the German Heinz Nixdorf Recall MultiGeneration study under steady-state, formyl-methionyl-leucyl-phenylalanine-, CXCL1-, and CXCL8-stimulated conditions. Comparable values were obtained in an independent laboratory from a cohort in Belgium, demonstrating the robustness and transferability of the assay. In a do...
Source: Journal of Immunology - Category: Allergy & Immunology Authors: Tags: J Immunol Source Type: research
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