High nuclear MSK1 is associated with longer survival in breast cancer patients

ConclusionsHigh MSK1 is associated with improved breast cancer-specific survival in early stage invasive breast cancer patients, and has additional prognostic value in HER2-negative and non-basal like disease. Although not an independent marker of outcome, we believe such findings and significant associations with well-established negative prognostic factors (age, grade, Nottingham Prognostic Index, hormone receptor status, time to distant metastasis, recurrence and triple-negative/basal-like status) warrant further examination and validation in independent patient cohorts.

http://link.springer.com/10.1007/s00432-018-2579-7

Source: Journal of Cancer Research and Clinical Oncology - January 11, 2018 Category: Cancer & Oncology Source Type: research