The preliminary study on expression and clinical value of Platelet-derived growth factor BB, Hypoxia inducible factor-1 α and C-C motif chemokine receptor-2 in the peripheral blood during the pathogenesis of Graves disease.

CONCLUSION: CCR2 positive macrophages may induce the expression of PDGF-BB through HIF-1α signal, and the high expression of PDGF-BB may be involved in the pathogenesis of GD. PMID: 29319128 [PubMed - as supplied by publisher]
Source: Endokrynologia Polska - Category: Endocrinology Authors: Tags: Endokrynol Pol Source Type: research