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Omalizumab in patients with severe uncontrolled asthma: well-defined eligibility criteria to promote asthma control

ABSTRACT Tuberculosis treatment remains a challenge due to the need to consider, when approaching it, the context of individual and collective health. In addition, social and economic issues have been shown to be variables that need to be considered when it comes to treatment effectiveness. We conducted a critical review of the national and international literature on the treatment of tuberculosis in recent years with the aims of presenting health care workers with recommendations based on the situation in Brazil and better informing decision-making regarding tuberculosis patients so as to minimize morbidity and interrupt disease transmission.RESUMO O tratamento da tuberculose permanece um desafio em fun ção da necessidade de que, em sua abordagem, seja considerado o contexto da saúde do indivíduo e da saúde coletiva. Adicionalmente, as questões sociais e econômicas têm-se mostrado como variáveis a ser consideradas na efetividade do tratamento. Ao revisarmos de forma crítica a literatura c ientífica nacional e internacional sobre o tratamento da tuberculose nos últimos anos, tivemos como objetivos apresentar aos profissionais da área de saúde as recomendações baseadas na realidade brasileira e fornecer os subsídios necessários para a melhor tomada de decisão frente ao pacient e com tuberculose, de modo a minimizar a morbidade e interromper a trans...
Source: Jornal Brasileiro de Pneumologia - Category: Respiratory Medicine Source Type: research

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Abstract The genus Hylocereus (family Cactaceae) includes about 16 species. Now its reputation is spreading everywhere in the world due to its fruit (pitaya or pitahaya or dragon fruit), which is one of the most popular and widely used functional foods in the world. The fruit is a wealthy provenance of vitamins, minerals, antioxidants, and fiber. The ethno‐pharmacological history of this genus indicated that it possesses antioxidant, anticancer, antimicrobial, hepato‐protective, antihyperlipidemic, antidiabetic, and wound healing activities. Furthermore, it has been used for the treatment of cough, asthma, hyperactivit...
Source: Journal of Food Biochemistry - Category: Food Science Authors: Tags: REVIEW Source Type: research
CONCLUSION: Adults with AD had increased cutaneous, respiratory, multiorgan, and systemic infections, which were associated with a considerable cost burden. PMID: 29273131 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
AbstractPurposeHIV is associated with chronic obstructive pulmonary disease (COPD) in high resource settings. Similar relationships are less understood in low resource settings. We aimed to estimate the association between HIV infection, tuberculosis, and COPD in rural Uganda.MethodsThe Uganda Non-communicable Diseases and Aging Cohort study observes people 40  years and older living with HIV (PLWH) on antiretroviral therapy, and population-based HIV-uninfected controls in rural Uganda. Participants completed respiratory questionnaires and post-bronchodilator spirometry.ResultsAmong 269 participants with spirometry, m...
Source: Lung - Category: Respiratory Medicine Source Type: research
AbstractIn the last decade, autosomal recessive interleukin-12 receptor β1 (IL-12Rβ1) deficiency, the most common cause of Mendelian susceptibility to mycobacterial disease (MSMD), has been diagnosed in a few children and adults with severe tuberculosis in Iran. Here, we report three cases referred to the Immunology, Asthma and Allergy ward at the National Research In stitute of Tuberculosis and Lung Diseases (NRITLD) at Masih Daneshvari Hospital from 2012 to 2017 with Mycobacterium tuberculosis and non-tuberculous mycobacteria infections due to defects in IL-12Rβ1 but with different clinical manifestations....
Source: Immunogenetics - Category: Genetics & Stem Cells Source Type: research
Conclusion: A subset of PTB patients can later develop asthma, probably after the enhanced level of Th1 lymphocytes has reduced to normal with anti-tubercular therapy. These patients are likely to benefit with the use of inhaled corticosteroids along with other bronchodilator therapy
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Conclusion: Management of IPF requires a comprehensive approach, which includes the identification and treatment of comorbid conditions to optimize patient outcomes.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Diffuse Parenchymal Lung Disease Source Type: research
Publication date: Available online 12 November 2017 Source:The Lancet Author(s): Robert W Aldridge, Alistair Story, Stephen W Hwang, Merete Nordentoft, Serena A Luchenski, Greg Hartwell, Emily J Tweed, Dan Lewer, Srinivasa Vittal Katikireddi, Andrew C Hayward Background Inclusion health focuses on people in extremely poor health due to poverty, marginalisation, and multimorbidity. We aimed to review morbidity and mortality data on four overlapping populations who experience considerable social exclusion: homeless populations, individuals with substance use disorders, sex workers, and imprisoned individuals. Methods For th...
Source: The Lancet - Category: General Medicine Source Type: research
Ultraviolet Irradiation of Blood: "The Cure That Time Forgot"? Adv Exp Med Biol. 2017;996:295-309 Authors: Hamblin MR Abstract Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases including septicemia, pneumonia, tuberculosis, arthritis, asthma and even poliomyelitis. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. However with the development of antibiotics, UBI use declined and it has now been called "the cure that time forgot". Later studies were mostly performed by...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Conclusions Asthma and COPD patients are prone to anxiety and depression more than normal populations, this lead to poor outcomes of both diseases. Summary at a glance This study included 420 subjects divided into three groups: Group I asthmatic (150) patients, group II COPD patients (150) and control group contain (120) healthy subjects. All patients and healthy subjects were instructed to answer the questionnaire of HADS. Anxiety and depression scales were calculated with prevalence of each. Anxiety and depression were more common in people with asthma and COPD.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
Conclusion H. pylori infection was infrequently associated in asthmatic patients and has a prominent inverse relationship with severity of bronchial asthma and better control of the disease.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - Category: Respiratory Medicine Source Type: research
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