Omalizumab in patients with severe uncontrolled asthma: well-defined eligibility criteria to promote asthma control

ABSTRACT Tuberculosis treatment remains a challenge due to the need to consider, when approaching it, the context of individual and collective health. In addition, social and economic issues have been shown to be variables that need to be considered when it comes to treatment effectiveness. We conducted a critical review of the national and international literature on the treatment of tuberculosis in recent years with the aims of presenting health care workers with recommendations based on the situation in Brazil and better informing decision-making regarding tuberculosis patients so as to minimize morbidity and interrupt disease transmission.RESUMO O tratamento da tuberculose permanece um desafio em fun ção da necessidade de que, em sua abordagem, seja considerado o contexto da saúde do indivíduo e da saúde coletiva. Adicionalmente, as questões sociais e econômicas têm-se mostrado como variáveis a ser consideradas na efetividade do tratamento. Ao revisarmos de forma crítica a literatura c ientífica nacional e internacional sobre o tratamento da tuberculose nos últimos anos, tivemos como objetivos apresentar aos profissionais da área de saúde as recomendações baseadas na realidade brasileira e fornecer os subsídios necessários para a melhor tomada de decisão frente ao pacient e com tuberculose, de modo a minimizar a morbidade e interromper a trans...
Source: Jornal Brasileiro de Pneumologia - Category: Respiratory Medicine Source Type: research

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(Natural News) An Indian study tested the antimycobacterial, antibacterial, and leishmanicidal properties of three different species of orchids from the northern province of Arunachal Pradesh. Fractions and extracts from these medicinal plants offered alternative therapies for asthma, malaria, and tuberculosis, and visceral leishmaniasis. The tested plants are the foxtail orchid (Rhynchostylis retusa), duan sui zhu jing...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
ConclusionAn increased risk of TB development may persist for 3 years after stopping the ICS and the risk is higher in patients with COPD regardless of the type of ICS used.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Mur LA, Huws SA, Cameron SJ, Lewis PD, Lewis KE Abstract The lung microbiome has been shown to reflect a range of pulmonary diseases-for example: asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Studies have now begun to show microbiological changes in the lung that correlate with lung cancer (LC) which could provide new insights into lung carcinogenesis and new biomarkers for disease screening. Clinical studies have suggested that infections with tuberculosis or pneumonia increased the risk of LC possibly through inflammatory or immunological changes. These have now been supersede...
Source: Ecancermedicalscience - Category: Cancer & Oncology Tags: Ecancermedicalscience Source Type: research
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
Publication date: Available online 1 September 2018Source: International Journal of PharmaceuticsAuthor(s): Mohammad A.M. Momin, Ian G. Tucker, Shyamal C. DasAbstractTuberculosis (TB) is a major global health burden. The emergence of the human immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB control. Pulmonary delivery of drugs using dry powder inhalers (DPI) is an emerging approach to treat TB. In comparison with the conventional pulmonary delivery for asthma and chronic obstructive pulmonary disease (COPD), TB requires high dose delivery to the lung. However, high dose delivery depends ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
The treatment of Mycobacterium tuberculosis infection is often viewed in isolation from other human microbial symbionts. Understandably, the clinical priority is eliminating active or latent tuberculosis (TB) in patients. With the increasing resolution of molecular biology technologies, it is becoming apparent that antibiotic treatment can perturb the homeostasis of the host microbiome. For example, dysbiosis of the gut microbiota has been associated with an increased risk of the development of asthma, obesity and diabetes.
Source: Tuberculosis - Category: Respiratory Medicine Authors: Tags: Review Source Type: research
Bharath A Chhabria, Ritesh Agarwal, Mandeep Garg, Nalini Gupta, Amanjit Bal, Sahajal Dhooria, Inderpaul Singh SehgalLung India 2018 35(5):421-424 Mediastinal cysts are mostly congenital, but rarely, infections and malignancies can cause cystic degeneration of enlarged mediastinal lymph nodes. Diagnosis is challenging as the presenting symptoms are nonspecific. Surgical resection is the reference modality both for diagnosis and management. Secondary infection of mediastinal bronchogenic cyst with Mycobacterium tuberculosis is rare. Herein, we describe a young male who was managed as bronchial asthma with inhalational bronc...
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
ConclusionsA history of asthma or sinonasal disease may modulate immunological response to reduce incidence of active TB in the adult population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
CONCLUSION: These results indicate that children born in high TB burden foreign countries should be considered a high-risk group for LTBI in South Korea; the inclusion of these children in LTBI screening should be considered. PMID: 30095331 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
ConclusionsTechnology advances combined with basic transportation economics and adherence to civil rights laws, will steer transportation providers into offering cooperatively coordinated accessible mobility network. I’ll close with a list of resources.
Source: Journal of Transport and Health - Category: Occupational Health Source Type: research
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