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The role of Nrf2 signaling in counteracting neurodegenerative diseases

This article is protected by copyright. All rights reserved.
Source: FEBS Journal - Category: Research Authors: Tags: Review Article Source Type: research

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You're reading 7 Reasons To Meditate, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Do you always feel tired, stressed, and angry? Are you impulsive and can`t seem to stop snapping at people for the wrong reasons? If you say Yes, then you have to meditate more often. Why You Must Meditate Meditation is one of the best physical and spiritual activities you can gift yourself. For just 10 minutes each day, you can improve your mood, boost your energy and increase tranquility. But it`s not just about that. Researchers have ...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness psychology self improvement alzheimer's health benefits of meditation meditate pickthebrain sleep aid Source Type: blogs
ConclusionsMatrine may be used to treat prostate cancer patients to increase the levels of GADD45B to inhibit tumor invasion and improve patient survivals.
Source: The Prostate - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract ObjectivesThe use of doxorubicin, an antineoplastic medication used for the treatment of cancers via mechanisms that prevent replication of cells or lead to their death, can result in damage to healthy cells as well as malignant. Among the affected cells are mesenchymal stem cells (MSCs), which are involved in the maintenance and repair of tissues in the body. This review explores the mechanisms of biological effects and damage attributed to doxorubicin on MSCs. The PubMed database was used as a source of literature for this review. Key findingsDoxorubicin has the potential to lead to significant and irreversible ...
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: Review Source Type: research
This article is part of the Special Issue “Vascular Dementia”. We propose that hyperhomocysteinemia (HHcy) results in a pro‐inflammatory response at the vasculature, which activates the matrix metalloproteinase MMP9. MMP9 subsequently cleaves the a‐b dystroglycan complex, leading to disruption of the astrocytic connection with the vasculature. MMP9 also degrades the dystrophin Dp71 anchoring complex, resulting in the down‐regulation of astrocytic end‐foot channels. The end result of the end‐foot disruption is impaired potassium homeostasis in the brain and impaired neurovascular coupling.
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: Review Source Type: research
DEMENTIA is an umbrella term for a collection of symptoms that result from damage to the brain caused by different diseases - for example Alzheimer ’s. There is currently no cure available, but expert believe there are ways of reducing the risk of it developing.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: Without otologic intervention, cleft palate children in resource-deprived settings suffer type B tympanometry and failed OAE results with similar to increased incidences to other studied cleft palate populations with otologic interventions available. PMID: 29351047 [PubMed - in process]
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
This study sought to characterize the respiratory profile of 23 children with unilateral cleft lip and palate, aged 7-12 years, who had undergone cleft lip and nasal repair at age 3-4 months and palatoplasty at 12-15 months, with a particular focus on evaluating the presence of OSAS in children with CLP. Polysomnography was performed and findings were analyzed descriptively. We found a mean and median for apnea/hypopnea index (AHI) of 1.11/h (SD = 0.78) and 0.9/h, respectively. The mean obstructive apnea index (OAI) was 0.27/h (SD = 0.38) and the median, 0.1/h. Nearly 30% of patients had an AHI above 1.4 events/h. There wa...
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
CONCLUSIONS: The present study describes an easy method to monitor lingual pressure that succeeded in measuring such changes throughout 3 palatoplasties and confirming the acute rise in lingual pressure and the potential danger posed to the tongue and the airway through the use of the Dingman. PMID: 29351037 [PubMed - in process]
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
This study was conducted by surveying layperson volunteers in public community settings. PARTICIPANTS: 108 layperson volunteers were randomly surveyed. MAIN OUTCOME MEASURES: The primary outcome measure was a reported lip or nose asymmetry by the volunteers. Proportions and corresponding 95% confidence intervals were obtained to estimate the probability of reporting an asymmetry at 3- and 10-second intervals. RESULTS: After 3- and 10-second exposure, labial asymmetry was perceived by ≥50% of subjects at 2 mm (62%, P = .001) and 1 mm (89%, P
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
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