Expanded genomic profiling of circulating tumor cells in metastatic breast cancer patients to assess biomarker status and biology over time.

Conclusions: We demonstrate an approach for complete isolation of EPCAM-positive CTCs and downstream comprehensive transcriptional/genomic characterization to examine the biology and assess breast cancer biomarkers in these cells over time. PMID: 29311117 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29311117?dopt=Abstract

Source: Clinical Cancer Research - January 8, 2018 Category: Cancer & Oncology Authors: Magbanua MJM, Rugo HS, Wolfe DM, Hauranieh L, Roy R, Pendyala P, Sosa E, Scott JH, Lee JS, Pitcher BN, Hyslop TM, Barry WT, Isakoff SJ, Dickler MN, Van't Veer LJ, Park JW Tags: Clin Cancer Res Source Type: research