Comorbidities in Australian women with hormone-dependent breast cancer: a population-based analysis.
CONCLUSION: Comorbid conditions are more likely to develop in women who have been diagnosed with hormone-dependent breast cancer than in women without cancer. Our results further support the need to develop appropriate models of care to manage the multiple chronic disorders of breast cancer survivors. PMID: 29320669 [PubMed - in process]
Chunbo Yang, Sophia Kelaini, Rachel Caines, Andriana Margariti
Publication date: 15 January 2019Source: Journal of Molecular Structure, Volume 1176Author(s): S. Murugavel, C. Ravikumar, G. Jaabil, Ponnusamy AlagusundaramAbstractPrevious research studies confirm that molecules containing 1,2,3-triazole moiety are potential anticancer agents which elevates effectiveness and reduces drug resistance. Present study was aimed to evaluate the anticancer activity of the synthesized novel title compound 2-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-4-(2-chlorophenyl)-6-methoxypyridine (BTCP). The structural and spectral characteristics of BTCP were studied and compared with DFT results. NBO, HOM...
CONCLUSIONS: Contrary to our hypothesis, there was a tendency for older adults to have better outcomes than younger, independent of the diagnostic criteria applied. PMID: 30230916 [PubMed - as supplied by publisher]
CONCLUSION: VR was helpful in reducing BoNT procedure-related discomfort in a majority of patients. Challenges with VR setup, patient tolerance, and selecting viewing experiences were identified to guide further research and use of VR in a clinical environment. PMID: 30223406 [PubMed - as supplied by publisher]
Authors: Fisher MT, Zigler CK, Houtrow AJ Abstract PURPOSE: To evaluate variables that modulate pain during intramuscular botulinum toxin A injections in children. METHODS: As part of a Quality Improvement project, this retrospective analysis compared reported pain during and five minutes post injections with patient and procedural variables using subgroup and regression analyses (N= 593 procedures with 249 unique patients). RESULTS: Mean procedural pain for all procedures (n= 563) was 3.8 ± 3.0. Most children reported no pain (83.8%) or mild pain (12.1%) five minutes after the procedure. Provider, p...
WOMEN who have a diet high in gluten during pregnancy could increase the risk of their children suffering from diabetes, a study suggested yesterday. The research examined tens of thousands of pregnancies and found an increased risk of Type 1 diabetes.
Conclusion Based on our findings it seems that MSU classification can be used in patients' selection to achieve the best treatment outcome after intradiscal ozone injection among patients with lumbar disc herniation. PMID: 30227808 [PubMed - as supplied by publisher]
Publication date: Available online 19 September 2018Source: Advances in Biological RegulationAuthor(s): Mariana L. Oliveira, Padma Akkapeddi, Daniel Ribeiro, Alice Melão, João T. BarataAbstractInterleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. In their absence, severe combined immunodeficiency occurs. By contrast, excessive IL-7/IL-7R-mediated signaling can drive lymphoid leukemia development, disease acceleration and resistance to chemotherapy. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, u...
Simon Thompson, 32, from Kent, was rushed to hospital when a 'dental abscess' failed to improve despite antibiotics. He was later diagnosed with advanced Non Hodgkin's lymphoma.
From 2011 to 2016, expenditure on cancer drugs in the United States rapidly accelerated. The first prospective study of its kind tallies the numbers.Medscape Medical News
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