Differentiation of Inflammatory From Fibrotic Ileal Strictures among Patients with Crohn's Disease Based on Visual Analysis: Feasibility Study Combining Conventional B-Mode Ultrasound, Contrast-Enhanced Ultrasound and Strain Elastography

The aim of this pilot study was to assess prospectively the feasibility of conventional B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) combined with real-time strain elastography (SE) in the differentiation of inflammatory from fibrotic ileal strictures among patients with Crohn's disease (CD) based on visual analysis. Twenty non-consecutive patients (15 male and 5 female; mean age  ± standard deviation, 40.2 ± 10.22 y) with CD and stricture of the terminal ileal loop were scanned by conventional B-mode US and CEUS and, subsequently, by real-time SE.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research

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Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Authors: Goyal P, Shah J, Gupta S, Gupta P, Sharma V Abstract Introduction: Intestinal tuberculosis (ITB) and Crohn's disease (CD) have similar clinical presentation, but require different treatment approaches. Despite advances in various endoscopic, imaging, microbiological and histological techniques, the differentiation of these two entities is often difficult. Newer radiological and image acquisition modalities have now become indispensable tools for evaluation of these two diseases. Areas covered: This review summarizes the currently available literature on various radiological investigations to differentiate ...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Crohn's disease and ulcerative colitis are chronic inflammatory diseases that lead to progressive bowel damage including the development of stricturing and penetrating complications. Increasingly, cross-sectional imaging with computed tomography or magnetic resonance scans have emerged as leading tools to: (1) assess disease activity; (2) monitor response to therapy or disease recurrence; and (3) identify disease-related complications. Several validated radiological scoring systems have been developed to quantify cross-sectional and longitudinal inflammatory burden in these diseases and to monitor response to treatment. Bo...
Source: Gastrointestinal Endoscopy Clinics of North America - Category: Gastroenterology Authors: Source Type: research
fmann K Abstract A 37-year-old male patient with Crohn's disease and multiple liver hemangiomas was referred to our hospital for an atypical hypervascular hepatic lesion detected on an external magnetic resonance imaging (MRI) scan. The patient was otherwise well and had no history of any liver disease. Liver values and tumor markers were normal. Contrast-enhanced ultrasound confirmed multiple hemangiomas in different liver segments and a hypervascular tumor with a hypovascular rim in segment II/IV. Repeat MRI showed a strongly enhancing neoplasm of 2.6 cm with a texture distinctly different from the otherwise r...
Source: Zeitschrift fur Gastroenterologie - Category: Gastroenterology Authors: Tags: Z Gastroenterol Source Type: research
Authors: Wright EK, Ding NS, Niewiadomski O Abstract Australia has one of the highest incidence rates of inflammatory bowel disease (IBD) in the world. Early diagnosis and treatment for IBD is critical. For Crohn disease, in particular, this may change the natural history of disease and reduce disability. Faecal calprotectin is a sensitive test that can be used by primary care physicians to assist in determining which patients with gastrointestinal symptoms may have IBD. This allows for prompt identification of patients who may benefit from endoscopy. Regular re-evaluation of disease status with strategies that can...
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
​BY MARK GRANT, DO, &SARAH CARIGNAN, PA-CThe patient had been playing a round of golf a week earlier, and thought he had strained a muscle in his right lower back while swinging a golf club. The patient continued his golf workouts throughout the week, which included lifting weights and swinging a golf club with minimal pain.​The day prior to ED presentation, he began having worsening right-sided back pain, and began ibuprofen and ice treatment, which helped minimally. The patient woke up experiencing worsening back pain that radiated from his right flank to his right lower abdominal area. He reported increased pain...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
379Objectives: Crohn’s disease (CD) is a lifelong chronic inflammatory condition resulting in a requirement for frequent clinical and endoscopic reassessment. Multispectral optoacoustic tomography (MSOT), a new technique for analysis of haemoglobin and oxygenation in tissues, was tested in patients with CD as a non-invasive alternative to predict intestinal disease activity.Methods: In this single center, investigator-initiated, cross-sectional diagnostic study, n=108 patients with confirmed CD were imaged by MSOT. The ethics committee of the University of Erlangen-Nürnberg granted approval for the study, it was...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Gastrointestinal Nuclear Medicine Source Type: research
AbstractBackgroundLittle is known about changes in the imaging appearances of the bowel and mesentery over time in either pediatric or adult patients with newly diagnosed small bowel Crohn disease treated with anti-tumor necrosis factor-alpha (anti-TNF- α) therapy.ObjectiveTo define how bowel ultrasound findings change over time and correlate with laboratory inflammatory markers in children who have been newly diagnosed with pediatric small bowel Crohn disease and treated with infliximab.Materials and methodsWe included 28 pediatric patients treated with infliximab for newly diagnosed ileal Crohn disease who underwen...
Source: Pediatric Radiology - Category: Radiology Source Type: research
The aim of the study described here was to assess whether the analysis of time –intensity curves obtained after microbubble contrast agent injection could differentiate inflammatory from fibrotic ileal strictures among patients with Crohn's disease. Sixty-five consecutive patients (40 male and 25 female; mean age ± SD, 42.2 ± 12.22 y) with stricture of the terminal il eal loop from Crohn's disease were scanned after microbubble injection. Time–intensity curves were obtained from quantitative analysis, and peak enhancement, rise time, time to peak, area under the time&ndash...
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Original Contribution Source Type: research
It was a cloudy, September day at the Country Club of Miami in South Florida. Jake Goodstat, a high school sophomore and varsity golf player, approached the ninth green. He walked up to his ball with putter in hand, took a deep breath and gently tapped the ball to make the putt. He says this was the hole where he cinched second place in the 2016 South Florida Junior Golf Tournament. “It was the greatest feeling in the world to know that I placed,” recalls Jake, a Florida teen who underwent surgery two months prior to treat his Crohn’s disease. “Before my surgery, I...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories Athos Bousvaros Center for Inflammatory Bowel Disease (IBD) Crohn's disease Robert Shamberger Source Type: news
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