Behavioral fragmentation in the D1CT-7 mouse model of Tourette's syndrome.

CONCLUSION: The results of this study show that the D1CT-7 mouse model is subjected to a behavioral fragmentation, with repercussions going beyond the simple tic-like phenomenon. These phenotypes are strikingly akin to behavioral problems observed in patients with TS and further validate the power of this model in summarizing pivotal behavioral aspects of TS. PMID: 29314714 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29314714?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - January 3, 2018 Category: Neuroscience Authors: Santangelo A, Bortolato M, Mosher LJ, Crescimanno G, Di Giovanni G, Cassioli E, Ricca V, Casarrubea M Tags: CNS Neurosci Ther Source Type: research