Dexmedetomidine mitigates CLP-stimulated acute lung injury via restraining the RAGE pathway.
CONCLUSION: Our studies demonstrated that DEX attenuates the aggravation of sepsis-stimulated ALI via down regulation of RAGE pathway, which has a potential value in the clinical therapy.
PMID: 29312480 [PubMed]
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research