BK channels blockage inhibits hypoxia ‐induced migration and chemoresistance to cisplatin in human glioblastoma cells

In conclusion, our data show that BK channels promote several aspects of the aggressive potential of GBM cells induced by hypoxia, such as migration and chemoresistance to cisplatin, suggesting it as a potential therapeutic target in the treatment of GBM. This article is protected by copyright. All rights reserved

Source: Journal of Cellular Physiology - January 10, 2018 Category: Cytology Authors: Paolo Rosa, Luigi Catacuzzeno, Luigi Sforna, Giorgio Mangino, Silvia Carlomagno, Gabriella Mincione, Vincenzo Petrozza, Giuseppe Ragona, Fabio Franciolini, Antonella Calogero Tags: ORIGINAL RESEARCH ARTICLE Source Type: research