What Cardiologists Need to Know About New Diabetes Drugs What Cardiologists Need to Know About New Diabetes Drugs
Drs O'Donoghue and McGuire discuss the data on the various SGLT2 inhibitors and GLP1 receptor agonists and when to consider prescribing them to your patients with diabetes.theheart.org on Medscape
TYPE 2 diabetes can be managed by cutting down on highly calorific and sugary foods, but adding certain ingredients to your diet can also help. These two popular cooking ingredients could help to lower blood sugar and control diabetes symptoms.
CONCLUSIONS: The 2013 PCE-ASCVD or 1991 Framingham should be used as CVD risk models in Australian. However, the CVD high risk threshold for initiating CVD primary preventive therapy requires reconsideration. PMID: 30656697 [PubMed - as supplied by publisher]
Authors: Adie S, Harris I, Chuan A, Lewis P, Naylor JM Abstract The minimum requirements for total knee arthroplasty (TKA) are significant, prolonged symptoms with supporting clinical and radiological signs. Despite interest in screening tools, there is limited evidence for a specific symptom threshold that justifies surgery. Non-operative treatments including medications, exercise and weight loss are unlikely to reverse radiographic changes, but they may improve symptoms and delay the need for surgery. Many patient factors such as mental health and obesity affect both the level of symptomatic improvement after sur...
Authors: Titmuss A, Davis EA, Brown A, Maple-Brown LJ PMID: 30656687 [PubMed - as supplied by publisher]
AbstractWe herein report two cases of advanced stage rapidly progressive diabetic nephropathy that were effectively treated with combination therapy including renin –angiotensin–aldosterone system (RAS) blocker [angiotensin II receptor blocker (ARB)], glucagon-like peptide-1 (GLP-1) receptor agonist and sodium glucose transporter-2 (SGLT-2) inhibitor. A 30-year-old woman with advanced stage diabetic nephropathy [estimated glomerular filtration rate (eGFR): 20.7 mL/min/1.73 m2; proteinuria: 13.2 g/gCr], showing a rapidly progressive pattern (annual eGFR change: − 60.0 mL/min/1.7...
ConclusionsMedical comorbidities can complicate the postoperative course for patients undergoing Achilles tendon repair, which increases the cost of care and duration of treatment. A better understanding of the relationship between each medical comorbidity and surgical site infections following Achilles tendon repair may be ascertained with additional prospective studies, thus, allowing for a more accurate evaluation and stratification of surgical candidates to improve patient outcomes.Level of evidenceRetrospective cohort study, Level III.
In conclusion, GLP-1 intervention can change the proliferation and autophagy status of islet β cells in mice, and thus protect the function of islet β cells. PMID: 30656925 [PubMed - as supplied by publisher]
Conclusiones. Los resultados evidenciaron una alta prevalencia de factores de riesgo cardiovascular en niños, mayor en el área urbana. Se requieren estrategias de salud pública adaptadas a la población rural y a la urbana. PMID: 30653869 [PubMed - in process]
DISCUSSIONS: This paper identifies a number of challenges in the existing categories of computational tools and consequently presents possible avenues for future research. Failure to address these issues will negatively impact on the adoption rate of the self-management tools and applications. PMID: 30653364 [PubMed - as supplied by publisher]
Drug companies routinely make hidden pacts with middlemen.