Proton beam therapy for skull base chordomas in 106 patients: A dose adaptive radiation protocol.

CONCLUSIONS: This study suggests that the probability of LC of skull base chordomas depends on postoperative GTV. The dose adaptive protocol achieves acceptable local control. Future studies should investigate whether further dose escalation to doses in excess of 74 Gy(RBE) would achieve better results.
PMID: 29310903 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - January 6, 2018 Category: Radiology Authors: Fung V, Calugaru V, Bolle S, Mammar H, Alapetite C, Maingon P, De Marzi L, Froelich S, Habrand JL, Dendale R, Noël G, Feuvret L Tags: Radiother Oncol Source Type: research