Hippocampal shape alterations in healthy young women with familial risk for unipolar depression

Although reduced hippocampal volume (HCV) is a common finding in depression, it is unclear whether the structural alterations leading to reduction of HCV are pre-existing risk factors before the onset of clinical symptoms or a cumulative process that begins with the onset of clinical symptoms. The aim of the present study was to understand the anatomical status of the hippocampus prior to the clinical symptoms in subjects with high familial risk for depression.

Source: Comprehensive Psychiatry - January 9, 2018 Category: Psychiatry Authors: Ece Durmusoglu, Onur Ugurlu, Sebnem Akan, Fatma Simsek, Gozde Kizilates, Omer Kitis, Burcu Aksoy Ozkul, Cagdas Eker, Kerry L. Coburn, Ali Saffet Gonul Source Type: research