Orthopedia homeobox is preferentially expressed in typical carcinoids of the lung

CONCLUSIONSOTP is specific for LCs because well‐differentiated nonlung NETs are negative for OTP. OTP preferentially stains TCs over ACs. In well‐differentiated NETs, OTP staining is highly specific for LCs, and in combination with a low Ki‐67 index, it suggests a pulmonary TC. Cancer Cytopathol 2018. © 2018 American Cancer Society.

Source: Cancer Cytopathology - January 9, 2018 Category: Pathology Authors: Krisztina Z. Hanley, Zachary J. Dureau, Cynthia Cohen, Dong M. Shin, Taofeek K. Owonikoko, Gabriel L. Sica Tags: Original Article Source Type: research