Another $15M for Spirosure's respiratory analysis device
Pleasanton, California-based Spirosure (previously known as Spirometrix) has raised $15 million in Series C-2 financing for its breath analysis device, according to a statement. The funding round was led by returning investor NGK Spark Plugs Co. Ltd. of Japan, as well as other unnamed investors.
Condition: Idiopathic Pulmonary Fibrosis Intervention: Sponsors: patientMpower Ltd.; Boehringer Ingelheim Not yet recruiting
This study proposes various risk factors for prehypertension and hypertension, and our findings can be used as a large-scale screening tool for controlling and managing hypertension.
ConclusionsWC and PA were considered the parameters most related to MetS by principals components analysis. The diagnosis of MetS presented an inverse relation with the spirometrics parameters. Elevation of BP and WC were the predictors of the CFV% reduction.
Condition: Burn Patients Intervention: Other: Physiotherapy Sponsor: Isra University Completed
Study Objectives:An oral appliance (OA) is a validated treatment for obstructive sleep apnea (OSA). However, therapeutic response is not certain in any individual and is a clinical barrier to implementing this form of therapy. Therefore, accurate and clinically applicable prediction methods are needed. The goal of this study was to derive prediction models based on multiple awake assessments capturing different aspects of the pharyngeal response to mandibular advancement. We hypothesized that a multimodal model would provide robust prediction.Methods:Patients with OSA (apnea-hypopnea index [AHI]> 10 events/h) were recru...
Peak expiratory flow (PEF) is a simple, efficient method for monitoring progression of idiopathic subglottic stenosis and predicting receipt of surgical intervention, researchers report.Reuters Health Information
CONCLUSIONS: In children with pectus excavatum without surgical indications, forced vital capacity, forced expiratory volume in 1 s and functional capacity assessed by the 6‑min walk test improved significantly after a 12-week supervised exercise program. The study showed that adherence to the exercise-based program was good for all patients. PMID: 30421282 [PubMed - as supplied by publisher]
ABSTRACTBackground and objectiveBronchial thermoplasty (BT) has been consistently shown to reduce symptoms, exacerbations and the need for reliever medication in patients with severe asthma. Paradoxically, no consistent improvement in spirometry has been demonstrated. It has been suggested that this is due to a reduction in peripheral resistance in small airways, not captured by spirometry. Therefore, in this study, we evaluate the response to BT using oscillometry.MethodsA total of 43 patients with severe asthma from two centres were evaluated at baseline, 6 weeks and 6 months post BT, using spirometry, ple...
CONCLUSIONS: During a short training period (up to 7 weeks), the use of gradual and constant inspiratory resistance during RMT improves exercise and spirometric parameters in a similar way. RMT did not have a considerable impact on breathing efficiency in maximal effort. PMID: 30411602 [PubMed - as supplied by publisher]
Authors: Koehler U, Hildebrandt O, Koehler N, Sohrabi K Abstract This review presents updated information on small airways in the pathogenesis of chronic obstructive respiratory diseases. The lungs have a branching structure, segmentally divided from trachea down to the alveoli (generations 1 - 23). Airways can be divided into a conducting (generations 1 - 16) and a respiratory zone (generations 17 - 23). Conducting zone is mainly for air transportation, respiratory zone for gas exchange. Increasing attention has been directed to the role of small airways in chronic obstructive respiratory diseases. The...