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KTU students are developing dissolving lenses for glaucoma treatment

(Kaunas University of Technology) Students' team from Kaunas University of Technology (KTU) is working on a development of dissolving contact eye lenses, which can be of great assistance for those suffering from glaucoma. According to statistics, glaucoma is the most common cause of preventable, irreversible blindness -- it is responsible for 12.3 percent of blindness worldwide. It is being estimated that by the year 2020 there will be almost 80 million people in the world suffering from the condition.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Abstract Glaucoma is the second leading cause of blindness after cataract and is heterogeneous in nature. Employing a genetic approach for the detection of the diseased condition provides an advantage that the gene responsible for the disease can be identified by genetic test. The availability of predictive tests based on the published literature would provide a mechanism for early detection and treatment. The genotype and phenotype information could be a valuable source for predicting the risk of the disease. To this end, a web server has been developed, based on the genotype and phenotype of myocilin mutation, w...
Source: Genomics - Category: Genetics & Stem Cells Authors: Tags: Genomics Source Type: research
-- Eye drops are a popular way to treat glaucoma, a group of diseases that, if untreated, can damage the optic nerve and lead to blindness. To be safe and effective, however, these eye drops must be used as prescribed by a doctor. The U.S. National...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
(University of British Columbia) Eye drops developed by UBC researchers could one day treat glaucoma while you sleep -- helping to heal a condition that is one of the leading causes of blindness around the world.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Conclusions: Visual disability at presentation among JOAG patients is high. This entails a huge economic burden, given their young age and associated social responsibilities.
Source: Journal of Glaucoma - Category: Opthalmology Tags: Online Articles: Brief Report Source Type: research
Authors: Mann C, Anders F, Liu H, Brockhaus K, Liu A, Grus FH, Pfeiffer N, Thanos S, Prokosch V Abstract INTRODUCTION: Glaucoma is characterised by progressive loss of retinal ganglion cells and axons. Experimental research has concentrated on understanding the pathophysiological mechanisms involved in glaucomatous damage. It is still a matter of debate whether neurons or capillaries are primarily damaged by elevated intraocular pressure (IOP). The aim of this study was to detect IOP-induced vascular changes in the vessels of the optic nerve head and the main vessels of the retina in vivo. METHODS: Experimental...
Source: Klinische Monatsblatter fur Augenheilkunde - Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Ramanjit Sihota, Dewang Angmo, Deepa Ramaswamy, Tanuj DadaIndian Journal of Ophthalmology 2018 66(4):495-505 Lowering of intraocular pressure is currently the only therapeutic measure for Glaucoma management. Many longterm, randomized trials have shown the efficacy of lowering IOP, either by a percentage of baseline, or to a specified level. This has lead to the concept of 'Target” IOP, a range of IOP on therapy, that would stabilize the Glaucoma/prevent further visual field loss, without significantly affecting a patient's quality of life. A clinical staging of Glaucoma by optic nerve head evaluation and pe...
Source: Indian Journal of Ophthalmology - Category: Opthalmology Authors: Source Type: research
Treatment TermsLow vision rehabilitation Author Erin Hull Overview Verdina Gillette-Simms was only 18 when she was diagnosed with glaucoma. Over time, the elevated eye pressure associated with the disease damaged her optic nerve and left her struggling to see clearly. Now 56, Gillette-Simms considers herself fortunate. She's been able to maintain her independence thanks to the low-vision tools and techniques she learned at the Duke Eye Center's low-vision rehabilitation program. Preview Image Content Blocks Header Living with Glaucoma Content" Every day is a different day, " said Gillette-Simms...
Source: dukehealth.org: Duke Health News - Category: Consumer Health News Authors: Source Type: news
Conclusions In conclusion, each of the MAPKs showed a specific spatio-temporal expression and activation pattern in the retina, ONH and optic nerve as a result of IOP elevation. These findings likely reflect the roles of the individual enzymes, and the cells in which they reside, in the developing pathology following IOP elevation. These data have implications for understanding the mechanisms of ocular pathology in diseases such as glaucoma.
Source: Molecular and Cellular Neuroscience - Category: Neuroscience Source Type: research
CONCLUSIONS: While continuing to advance control of cataract and AMD as the leading causes of blindness remains a high priority, overcoming barriers to uptake of refractive error services would address approximately half of the MSVI burden. New data on burden of presbyopia identify this entity as an important public health problem in this population. Additional research on better treatments, better implementation with existing tools and ongoing surveillance of the problem is needed. PMID: 29545417 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
Conclusions: This research showed that the proposed method using three statistics features achieves good performance for glaucoma detection. PMID: 29503753 [PubMed]
Source: Healthcare Informatics Research - Category: Information Technology Tags: Healthc Inform Res Source Type: research
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