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KTU students are developing dissolving lenses for glaucoma treatment

(Kaunas University of Technology) Students' team from Kaunas University of Technology (KTU) is working on a development of dissolving contact eye lenses, which can be of great assistance for those suffering from glaucoma. According to statistics, glaucoma is the most common cause of preventable, irreversible blindness -- it is responsible for 12.3 percent of blindness worldwide. It is being estimated that by the year 2020 there will be almost 80 million people in the world suffering from the condition.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Conclusion: A new regimen, in addition to standard treatment, for severe chemical burns is proposed. This involves tumor necrosis factor alpha (TNF-α) inhibition promptly after the accident (primarily for retinal neuroprotection), prophylactic maximal lowering of the intraocular pressure (starting immediately), and keratoprosthesis implantation in a later quiet state.
Source: Cornea - Category: Opthalmology Tags: Special Article Source Type: research
Authors: Schweitzer C Abstract Pseudoexfoliation syndrome is an age-related systemic disease that mainly affects the anterior structures of the eye. Despite a worldwide distribution, reported incidence and prevalence of this syndrome vary widely between ethnicities and geographical areas. The exfoliative material is composed mainly of abnormal cross-linked fibrils that accumulate progressively in some organs such as the heart, blood vessels, lungs or meninges, and particularly in the anterior structures of the eye. The exact pathophysiological process still remains unclear but the association of genetic and environ...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Herrero-Vanrell R Abstract Pathologies affecting the optic nerve and the retina are one of the major causes of blindness. These diseases include age-related macular degeneration (AMD), diabetic Retinopathy (DR) and glaucoma, among others. Also, there are genetic disorders that affect the retina causing visual impairment. The prevalence of neurodegenerative diseases of the posterior segment are increased as most of them are related with the elderly. Even with the access to different treatments, there are some challenges in managing patients suffering retinal diseases. One of them is the need for frequent interventi...
Source: Advanced Drug Delivery Reviews - Category: Drugs & Pharmacology Authors: Tags: Adv Drug Deliv Rev Source Type: research
Conclusion: A new regimen, in addition to standard treatment, for severe chemical burns is proposed. This involves tumor necrosis factor alpha (TNF-α) inhibition promptly after the accident (primarily for retinal neuroprotection), prophylactic maximal lowering of the intraocular pressure (starting immediately), and keratoprosthesis implantation in a later quiet state.
Source: Cornea - Category: Opthalmology Tags: Special Article Source Type: research
How common are dye eyes?The prevalence of dry eyes has been estimated to be 5-30% percent in persons aged 50 years and older, 7% of US adult population has been diagnosed with dry eye disease. The prevalence increases with age (2.7% in those 18 to 34 years old vs. 19% in those aged 75 years and older). Prevalence is higher in women than men (9% versus 4%).What are the risk factors for dry eye disease?- Advanced age- Female gender- Hormonal changes (primarily due to decreased androgens)- Systemic diseases (eg, diabetes mellitus, Parkinson disease)- Contact lens wear- Systemic medications (antihistamines, anticholinergi...
Source: Clinical Cases and Images - Blog - Category: Universities & Medical Training Authors: Tags: Ophthalmology Source Type: blogs
The review highlights common ophthalmic emergencies seen in the hospitalized geriatric patient. It describes key features of the ophthalmic examination, early identification, and treatment of ophthalmic emergencies, including transient monocular loss of vision with risk of future ischemic complications, central retinal artery occlusion, giant-cell arteritis, retinal detachment, acute angle closure glaucoma, orbital cellulitis, and orbital trauma. Research is ongoing regarding the best techniques to maximize visual outcome for these conditions. The benefits of surgical versus medical management for transient monocular blind...
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Systematic Review and Clinical Guidelines Source Type: research
ConclusionsThe damage to ganglion cells and eventually glaucomatous injury can occur via various mechanisms including baric trauma, ischemia and impact of metabolic toxins, which triggers an inflammatory process and secondary degeneration in the ONH.
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Authors: Chaudhary A, Salinas L, Guidotti J, Mermoud A, Mansouri K Abstract INTRODUCTION: Glaucoma is a leading cause of blindness worldwide. Intraocular pressure (IOP) lowering is the only effective treatment strategy. Traditional glaucoma surgeries are generally considered to be unpredictable and associated with a high rate of complications. This has led to the development of a novel XEN Gel Implant, a type of minimally invasive glaucoma surgery (MIGS), lowering the IOP without extensive surgical dissection. Areas Covered: A literature search was undertaken on PubMed using the terms XEN glaucoma, gelatin microste...
Source: Expert Review of Medical Devices - Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research
Authors: Cong L, Fu S, Zhang J, Zhao J, Zhang Y Abstract Primary open-angle glaucoma (POAG) with complex pathogenesis is one of the many major causes of blindness. It is widely accepted that the major cause of POAG is the dysregulation of the trabecular meshwork (TM), which regulates the resistance to aqueous humour outflow. Intraocular pressure is elevated with increasing outflow resistance in the conventional pathway, which consists of the TM and Schlemm's canal. The TM is a filter made up of extracellular matrix (e.g., collagens), most of which is organized into a network of beams covered by endothelial-like tra...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Glaucoma, an eye condition that can lead to blindness, affects a significant number of older adults. Could a household beverage help to shield us from it?
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news
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