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Kidney Injury Common After Non - Kidney Transplants in Children

High risk of AKI in first year after non - kidney solid organ transplant; in turn, increases CKD risk
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Cardiology, Gastroenterology, Nephrology, Pathology, Pediatrics, Pulmonology, Surgery, Critical Care, Journal, Source Type: news

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Todd and Lindsey Taylor had barely settled in at home in Syracuse, New York with their new baby, London, when their world turned upside down. London, who had seemed perfectly healthy at birth, woke up nine days later vomiting and struggling to breathe. They rushed her to their local children’s hospital. “The doctors did an ultrasound and found a large blood clot in her aorta that was blocking the flow of blood to her kidneys,” says Todd. “They said she was in near fatal condition when we arrived, but they put her on dialysis and were able to stabilize her.” Desperate for options The doctors in...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories blood clot Dr. Anne Hansen Dr. Heung-Bae Kim Midaortic Syndrome and Renovascular Hypertension (MAS/RVH) Program neonatal intensive care unit Source Type: news
Conclusion: Belatacept is a novel costimulation blocker that is devoid of the nephrotoxic properties of CNIs and has been shown to positively impact long-term graft survival and preserve renal allograft function in low-immunologic-risk kidney transplant recipients. Data regarding its use in patients who are broadly sensitized to human leukocyte antigens are scarce, and the increased risk of rejection associated with belatacept has been a deterrent to more widespread use of this immunosuppressive agent. This case serves as an example of a highly sensitized patient that has been successfully converted to a belatacept-based C...
Source: Case Reports in Nephrology and Dialysis - Category: Urology & Nephrology Source Type: research
Conclusion: These data suggests familial aggregation of IgA nephropathy, confirm the clinical and histopathological heterogeneity and raise the possibility of monogenic inheritance.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
Contributors : Petra Hruba ; Ondrej Viklicky ; Zdenek Krejcik ; Viktor Stranecky ; Faikah Gueler ; Alena Parikova ; Janka Slatinska ; Mariana Wohlfahrtova ; Ilja Striz ; Jiri Fronek ; Eva Honsova ; Jana MaluskovaSeries Type : Expression profiling by arrayOrganism : Homo sapiensBoth present hemagglutinins and anti HLA antibodies bind to vascular endothelial cells in kidney transplantation, however in some patients this antibody-endothelial interaction is not associated with obvious tissue injury. Mechanisms of this phenomenon called accommodation remain poorly understood. Illumina Human HT-12 v4 Expression BeadChips whole r...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Resumo Objetivo: Caracterizar o perfil de enfrentamento e qualidade de vida dos pacientes em lista de espera de transplante renal. M étodos: Estudo transversal, com abordagem quantitativa, foram entrevistados pacientes maiores de 18 anos, alfabetizados e em lista de espera de transplante renal. Foram excluídos os pacientes em espera de mais de um órgão. A apresentação dos resultados ocorreu pela estatística descritiva - di stribuição absoluta e relativa (n - %), bem como, pelas medidas de tendência central e de variabilidade, sendo que, o estudo da distri...
Source: Acta Paulista de Enfermagem - Category: Nursing Source Type: research
Cardiovascular disease (CVD) is a leading cause of mortality after kidney transplantation (KT). The potential role of the complement system in the pathogenesis of post-transplant CVD remains unexplored.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
AbstractPurposeThe number of simultaneous liver-kidney transplants (SLKT) performed in the USA has been rising. The Organ Procurement and Transplantation Network implemented a new policy governing SLKT that specifies eligibility criteria for candidates to receive a kidney with a liver, and creates a kidney waitlist “safety net” for liver recipients with persistent renal failure after transplant. This review explores potential impacts for liver patients and the kidney waitlist.Recent FindingsFactors that have contributed to the rise in SLKT including Model for End-stage Liver Disease (MELD)-based allocation, reg...
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research
AbstractPurpose of ReviewThis paper describes the background, rationale, and design of an NIH-funded, single-center study to test the impact of offering reimbursement for donor lost wages incurred during the post-nephrectomy recovery period on the live donor kidney transplant (LDKT) rate in newly evaluated kidney transplant candidates, to examine whether offering reimbursement for donor lost wages reduces racial disparity in LDKT rates, and to determine whether higher reimbursement amounts lead to higher LDKT rates.Recent FindingsLDKT is the optimal treatment for renal failure. However, living kidney donation has declined ...
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research
I am a physician. As a high-risk obstetrician (maternal-fetal medicine specialist) I pride myself on caring for women who are likely to become (or who are already) so ill that many others view caring for them as a burden. I help women achieve a safe pregnancy when colleagues have advised against pregnancy altogether. Whether it is the patient with such a complex surgical history that her cesarean delivery will include massive blood loss and a hysterectomy, or the patient with a history of liver transplant trying to carry a pregnancy for the fourth time (each unsuccessful as she struggles in and out of graft rejection), or ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Family Planning and Pregnancy Health Women's Health birth control Source Type: blogs
Conclusions: Bardoxolone methyl preserves kidney function and may delay the onset of ESRD in patients with T2D and stage 4 CKD.Am J Nephrol 2018;47:40 –47
Source: American Journal of Nephrology - Category: Neurology Source Type: research
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