Mood changes with methotrexate therapy for dermatologic disease

We describe two children who experienced mood changes with methotrexate treatment for lichen sclerosus with morphea overlap and psoriasis, with rapid resolution of these symptoms after methotrexate cessation. We also detail possible mechanisms underlying psychiatric changes with methotrexate therapy.

Source: Pediatric Dermatology - January 9, 2018 Category: Dermatology Authors: Trisha Bhat, Carrie C. Coughlin Tags: BRIEF REPORT Source Type: research