Risk Factors for Ventilator-Associated Events in a PICU*

Objective:
The term ventilator-associated events includes ventilator-associated condition, infection-related ventilator-associated complication, and ventilator-associated pneumonia. We sought to identify potential new risk factors for ventilator-associated condition and infection-related ventilator-associated complication in the PICU population.
Design:
Matched case control study.
Setting:
Children’s hospital at a tertiary care academic medical center.
Patients:
During the study period, 606 patients were admitted to PICU and ventilated more than 48 hours; 70 children met ventilator-associated condition criteria.
Interventions:
None.
Measurements and Main Results:
We applied the definition for ventilator-associated condition (i.e., a sustained increase in ventilator settings after a period of stable or decreasing support) to our database. Within ventilator-associated condition cases, 40 cases were infection-related ventilator-associated complication and 30 cases were noninfectious-related ventilator-associated condition. We identified 140 controls and matched to ventilator-associated condition cases with regard to age, immunocompromised status, and ventilator days to event. Patients with ventilator-associated condition had longer ICU stay versus controls; 24 days median (12–43 interquartile range) versus 7 days (4–14); (p

Source: Pediatric Critical Care Medicine - January 1, 2018 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research