Prenylated Coumarins of the Genus Citrus: an Overview of the 2006-2016 Literature Data.

Prenylated Coumarins of the Genus Citrus: an Overview of the 2006-2016 Literature Data. Curr Med Chem. 2018 Jan 04;: Authors: Genovese S, Taddeo VA, Epifano F, Fiorito S Abstract O-Prenyl coumarins (3,3-dimethylallyl, geranyl-, farnesyl- and related biosynthetic derivatives) represent a class of rarely occurring natural products. In the last two decades such secondary metabolites have been found to possess promising and effective pharmacological properties, mainly in terms of anti-cancer and anti-inflammatory properties. To date about 160 oxyprenylated coumarins have been extracted from plants, fungi, and bacteria. The genus Citrus have been demonstrated to be among the richest source of the title products. The aim of this comprehensive review is to make a survey of the in so far reported literature citations about the main O-prenyl coumarins found in this genus from phytochemical and pharmacological point of views and for which no surveys of the in so far reported literaute have been made. PMID: 29303071 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research