Editorial: Recent Advances in Pathophysiological Studies and Treatment of Epilepsy.

Editorial: Recent Advances in Pathophysiological Studies and Treatment of Epilepsy. Curr Neuropharmacol. 2018;16(1):3-4 Authors: Yin G, Yao G, Zhang K, Li B PMID: 29301484 [PubMed - in process]
Source: Current Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Neuropharmacol Source Type: research

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Publication date: Available online 14 August 2018Source: Journal of Neuroscience MethodsAuthor(s): Matthew S. Binder, Christian J. Hernandez-Zegada, Christian T. Potter, Nolan O. Suzanne, Joaquin N. LugoAbstractAlterations in early-life communicative behaviors are a common feature of neurodevelopmental conditions such as autism and epilepsy. One method of investigating communication in murine models is through analyzing ultrasonic vocalizations. These vocalizations are commonly recorded with either the Avisoft or the Ultravox recording programs. However, since no study has compared whether the systems are equally sensitive...
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
We report on a case with developmental delay and dysmorphic craniofacial features, and a novel~15.2 Mb interstitial deletion within 9q21.11q21.32 confirmed with array comparative genomic hybridization (aCGH). A twenty-two month old boy with inability to walk without support, absent speech, and attention deficit and hyperactivity disorder was seen in our clinic. His craniofacial examination revealed relative macrocephaly, facial asymmetry, frontal bossing, sparse medial eyebrows, hypertelorism, broad base to nose, smooth philtrum, large mouth, operated cleft lip and wide spaced teeth. The high resolution binding (HRB) chrom...
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
BACKGROUND AND PURPOSE: To identify predictors of seizure-related injury (SRI) and death in people with epilepsy (PWE) in a North Indian cohort. METHODS: This ambispective cohort study included PWE registered in an epilepsy clinic in Delhi between ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
We describe an 8-year-old male with a pathogenicUNC80 mutation, intellectual disability, hypotonia and epilepsy with severe central sleep apnea (213.5 events/h) on polysomnography (PSG). We also describe a 20-month-old female with aKCNJ11 mutation, neonatal diabetes and developmental delay who had severe central sleep apnea (131.1 events/h). Both patients had irregular respiratory patterns during sleep and wakefulness and were placed on empiric bilevel positive airway pressure therapy, which was well tolerated with resolution of abnormal respiratory control and hypercapnia. Patients withUNC80 andKCNJ11 gene mutations may h...
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
ConclusionRatings on the BRIEF, CBCL, and TRF are moderately to highly correlated, suggesting a (strong) link between executive and behavioral functioning. Subtle differences between parents and teachers ratings suggest different executive function demands in various settings.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 14 August 2018Source: Epilepsy &BehaviorAuthor(s): Pasquale Parisi, Vincenzo Belcastro, Alberto Verrotti, Pasquale Striano, D.G.A. Kasteleijn-Nolst Trenitè
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
(MedPage Today) -- News and commentary from the world of neurology and neuroscience
Source: MedPage Today Neurology - Category: Neurology Source Type: news
ConclusionWe noticed an increased utilization of eiEEG in elderly patients after the introduction of SEEG at our center. Overall, we found that eiEEG can help achieve good seizure outcomes in the elderly population. However, the one eiEEG-related mortality serves a word of caution about the potential risks in this population.
Source: Epilepsy and Behavior Case Reports - Category: Neurology Source Type: research
Publication date: Available online 13 August 2018Source: The Lancet PsychiatryAuthor(s): René S Kahn, Inge Winter van Rossum, Stefan Leucht, Philip McGuire, Shon W Lewis, Marion Leboyer, Celso Arango, Paola Dazzan, Richard Drake, Stephan Heres, Covadonga M Díaz-Caneja, Dan Rujescu, Mark Weiser, Silvana Galderisi, Birte Glenthøj, Marinus J C Eijkemans, W Wolfgang Fleischhacker, Shitij Kapur, Iris E Sommer, René S KahnSummaryBackgroundNo established treatment algorithm exists for patients with schizophrenia. Whether switching antipsychotics or early use of clozapine improves outcome in (first-epis...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
(Michigan State University) An aquarium fish that senses the Earth's magnetic field as it swims could help unlock how the human brain works and how diseases such as Parkinson's and other neurological disorders function. Michigan State University scientists are the first to discover a navigational gene in glass catfish called the electromagnetic-perceptive gene, or EPG, that responds to certain magnetic waves. They've already developed a way to use it to control movement in mice.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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