Electroconvulsive Therapy in America: The Anatomy of a Medical Controversyby Jonathan Sadowsky. New York, Routledge, 2017, 172 pp., $145.00 (hardcover).

Electroconvulsive Therapy in America: The Anatomy of a Medical Controversyby Jonathan Sadowsky. New York, Routledge, 2017, 172 pp., $145.00 (hardcover). Am J Psychiatry. 2018 Jan 01;175(1):84 Authors: Gambino M PMID: 29301430 [PubMed - in process]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research

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The objective of the present study was to evaluate BDNF levels across high and low intrinsic religiosity (IR) in depressed inpatients. Serum BDNF levels were evaluated from 101 depressed inpatients at hospital admission and 91 inpatients at discharge. Religiosity was assessed using a validated version of the Duke University Religion Index. High IR patients had significantly higher serum BDNF at discharge than do low IR (52.0 vs. 41.3 ng/mL, P = 0.02), with a Cohen’s d effect size difference of 0.56. High IR patients had a statistically significant increase in BDNF levels from admission to discharge (43.6 ± 22....
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Condition:   Depression Interventions:   Drug: Ketamine;   Drug: Midazolam Sponsor:   St Patrick's Hospital, Ireland Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Most of us have very specific, vivid ideas about what staying in a psychiatric hospital looks like. These ideas have likely been shaped by Hollywood or sensationalist news stories. Because how often do we hear about someone’s real-life stay at a psychiatric facility? If going to therapy is rarely talked about, the conversations surrounding psychiatric hospitals are virtually non-existent. So we tend to imagine wild, worst-case scenarios. To provide a more accurate picture, we asked several individuals who’ve been hospitalized to share what it was like for them. Of course, every person’s experience is diff...
Source: Psych Central - Category: Psychiatry Authors: Tags: Disorders General Stress Suicide Treatment Bipolar Disorder hope Hospitalization Inspiration Manic Episodes Psychiatric Hospital suicidal Source Type: news
We performed a comparative study of the effect of electroconvulsive therapy on anxiety in outbred rats and Sprague-Dawley rats with depressive-like disorder induced by exposure to ultrasound of variable frequency (20-45 Hz). The anxiogenic effect of therapy was revealed in elevated plus maze and open-field tests in both linear and non-lineal rats, but was more pronounced in linear animals. Differences between outbred rats and Sprague-Dawley rats by the anxiety level were demonstrated. These results suggest that electroconvulsive therapy should be used with cautious in patients with depression and comorbid anxiety disorders...
Source: Bulletin of Experimental Biology and Medicine - Category: Biology Source Type: research
CONCLUSION: The data possibly indicate that patients with TRD who receive ECT during inpatient treatment already have a more extensive psychiatric medication at admission. Also, psychiatric medication appears to be increased less prominently when ECT is performed. These findings and the possibly associated long-term benefits should be addressed in future research. PMID: 31489462 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - Category: Neurology Authors: Tags: Nervenarzt Source Type: research
Publication date: Available online 3 September 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Yurika Kobayashi, Eri Segi-NishidaAbstractApproximately one third of patients with depression remain treatment resistant with existing antidepressants, suggesting that the currently-available antidepressants cannot induce appropriate responses in the brains of all patients. Long-term exposure to adrenocorticotrophic hormone (ACTH) has been proposed as a model that mimics at least some aspects of clinical treatment-resistant depression in rodents. The purpose of this study was to explore potential causes of antidepres...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
CONCLUSIONS: Overall, TL assessed by PCR does not represent a useful biomarker for predicting the therapeutic outcomes or risk for selected cognitive deficits following ECT. PMID: 31477194 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Conclusions In line with other recent publications, our data suggest a very good benefit-to-risk ratio for ECT in incapable patients refusing the treatment, while at the same time the provision of ECT in such patients is rare in Germany. In light of the scarcity of treatment alternatives and the possible consequences of a refusal to perform ECT in life-threatening conditions, a general rejection of involuntary ECT does not seem ethically appropriate.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions Approximately 80% of the patients showed overall satisfaction with ECT irrespective of consent status. Relatives were more satisfied with ECT than patients. Electroconvulsive therapy can be a lifesaving treatment for severely depressed patients, and the subjective experience of involuntary patients should be taken into consideration when discussing involuntary ECT treatment.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
Conclusions The study provided support to the existing literature where cognitive improvement has been reported among individuals with schizophrenia after ECT. Future studies should consider the use of randomized controlled trials to examine the possible cognitive benefits of ECT. In a setting where there is a high volume of patients receiving ECT, the monitoring of patients' cognitive status through the course of ECT continues to be warranted and the Brief ECT Cognitive Screen may be useful as a quick measure to detect such ECT-related cognitive change.
Source: The Journal of ECT - Category: Psychiatry Tags: Original Studies Source Type: research
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