The detection of rotavirus in paediatric oncology patients with diarrhoea: the impact of rotavirus vaccine

Publication date: Available online 6 January 2018 Source:Journal of Hospital Infection Author(s): T. Akhtar, J. Cargill, C. Gerrard, F. Shaw, N.A. Cunliffe, R.P.D. Cooke, B. Pizer We reviewed seven year's data to examine stool testing for rotavirus in patents treated on a regional Paediatric Oncology Unit before and after the introduction of UK-wide rotavirus immunisation in July 2013. The prevalence of rotavirus positivity has diminished since the introduction of rotavirus immunisation, with 21 of 416 positive samples between 2010 and 2012, but only one positive test out of 122 samples in 2015 and 2016. Based on these results, we suggest there is very little utility for routine rotavirus testing in children and young people with cancer presenting with diarrhoea.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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Publication date: January 2020Source: Trends in Food Science &Technology, Volume 95Author(s): Ali Atamaleki, Mohsen Sadani, Amir Raoofi, Ali Miri, Saeed Gharibian Bajestani, Yadolah Fakhri, Zoha Heidarinejad, Amin Mousavi KhaneghahAbstractBackgroundThere is an increasing trend in the consumption of egg on a worldwide scale, however, it can be a source of potentially toxic elements (PTEs) which could threaten the health of consumers.Scope and approachThe related studies on the concentration of PTEs in eggs by databases including PubMed, Scopus, Web of Science and Embase in a global scale were retrieved and following met...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 8 November 2019Source: Food Research InternationalAuthor(s): Rodrigo Rezende Cardoso, Rafaela Oliveira Neto, Carolina Thomaz dos Santos D'Almeida, Talita Pimenta do Nascimento, Carolina Girotto Pressete, Luciana Azevedo, Hercia Stampini Duarte Martino, Luiz Claudio Cameron, Mariana Simões Larraz Ferreira, Frederico Augusto Ribeiro de BarrosAbstractUPLC-QTOF-MSE phenolic profile of kombuchas produced from the fermentation of green tea or black tea at 25°C for 10 days was investigated along with the determination of their antioxidant capacities, antibacterial and antiproliferativ...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 13 November 2019Source: Current Opinion in VirologyAuthor(s): Marta M Gaglia, Karl Munger
Source: Current Opinion in Virology - Category: Virology Source Type: research
Publication date: Available online 13 November 2019Source: Veterinary MicrobiologyAuthor(s): Linlin Li, Yun Zhang, Jiawen Dong, Junqing Zhang, Chunhong Zhang, Minhua Sun, Yongchang CaoAbstractDuck Tembusu virus (DTMUV) is a major pathogen of duck industry in China. In the current study, we generated different constructs containing envelope (E) protein, pre-membrane-envelope (prM-E) protein, and C-terminally truncated E protein of the DTMUV. The constructed proteins could induce specific antibody responses in young ducks. When ducklings were immunized with the constructed proteins, they were 100% protected against DTMUV inf...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: Available online 13 November 2019Source: Artificial Intelligence in MedicineAuthor(s): Ivan Lorencin, Nikola Anđelić, Josip Španjol, Zlatan CarAbstractIn this paper, the urinary bladder cancer diagnostic method which is based on Multi-Layer Perceptron and Laplacian edge detector is presented. The aim of this paper is to investigate the implementation possibility of a simpler method (Multi-Layer Perceptron) alongside commonly used methods, such as Deep Learning Convolutional Neural Networks, for the urinary bladder cancer detection. The dataset used for this research consisted of 1997 images of bl...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
This article discusses various educational interventions implemented in a new patient/family education program at the University of South Alabama Children's &Women's Hospital in Mobile, Alabama, for patients and family members of those newly diagnosed with pediatric cancer and other chronic illnesses. Tablet computers were made available to access reputable, easy to understand health resources during the educational processes upon diagnosis and continued treatment at the hospital. MedlinePlus, Patient Education Institute's X-Plain videos and other National Library of Medicine resources were available at the bedside and...
Source: Journal of Hospital Librarianship - Category: Databases & Libraries Tags: J Hosp Librariansh Source Type: research
In this study, we discovered that miR-561 expression was downregulated in human NSCLC tissues and cell lines. The overexpression of miR-561 inhibited NSCLC cell proliferation and cell cycle G1-S transition and induced apoptosis. The inhibition of miR-561 facilitated cell proliferation and G1-S transition and suppressed apoptosis. MiR-561 expression was inversely correlated with P-REX2a expression in NSCLC tissues. P-REX2a was confirmed to be a direct target of miR-561 by using a luciferase reporter assay. The overexpression of miR-561 decreased P-REX2a expression, and the suppression of miR-561 increased P-REX2a expression...
Source: Oncology Research - Category: Cancer & Oncology Tags: Oncol Res Source Type: research
Publication date: Available online 12 November 2019Source: Biosensors and BioelectronicsAuthor(s): Qiong Li, Sihui Zhou, Ting Zhang, Bei Zheng, Hongwu TangAbstractCancer, as the most invasive disease in the world, has led to an increasing amount of death year by year, so it is highly desired to develop a portable device to monitor the aberrant expression of biomarker in cancer patient. Here, we present a bio-photonic periodic nanostructures sensor chip assisted cyclic enzymatic amplification method to detect miRNA-21 with a detection limit of 55 fM. By employing biocompatible polydopamine nanospheres (PDANs) and DNaseⅠ...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 13 November 2019Source: Progress in Biophysics and Molecular BiologyAuthor(s): Kiel Hards, Cara Adolph, Liam K. Harold, Matthew B. McNeil, Chen-Yi Cheung, Adrian Jinich, Kyu Y. Rhee, Gregory M. CookAbstractCellular bioenergetics is an area showing promise for the development of new antimicrobials, antimalarials and cancer therapy. Enzymes involved in central carbon metabolism and energy generation are essential mediators of bacterial physiology, persistence and pathogenicity, lending themselves natural interest for drug discovery. In particular, succinate and malate are two major focal po...
Source: Progress in Biophysics and Molecular Biology - Category: Molecular Biology Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 004 A medical student who has just returned from their elective in Nepal presents with 1 week of bloody diarrhoea. He has been in the lowlands and stayed with a family in the local village he was helping at. It started three days before he left and he decided to get home on the plane in the hope it would settle. He is now opening his bowels 10x a day with associated cramps, fevers and has started feeling dizzy. Questions: Q1. What is dyse...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine amoebic dysentery bacillary dysentery e.histolytica entamoeba histolytica shigellosis Source Type: blogs
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