Oral administration of famciclovir for treatment of feline herpesvirus type 1 infections

Famciclovir, an oral prodrug of penciclovir, is an increasingly common treatment for FHV-1 –infected cats. Penciclovir is a nucleoside deoxyguanosine analog with potent antiviral activity against HSV-1, HSV-2, and varicella zoster virus, as well as variable in vitro activity against FHV-1. Penciclovir is consistently more potent than acyclovir, the only other drug used for the systemic treatment of cats infected with FHV-1. Penciclovir has low bioavailability in humans, and an oral prodrug, famciclovir, is used instead.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Respiratory Medicine Source Type: research