Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.7b00530

Source: Journal of Medicinal Chemistry - January 5, 2018 Category: Chemistry Authors: Sarah E. Huff, Faiz Ahmad Mohammed, Mu Yang, Prashansa Agrawal, John Pink, Michael E. Harris, Chris G. Dealwis and Rajesh Viswanathan Source Type: research