For Hospitals, No Benefit for Early Adoption of Financial Incentives
Hospitals with early adoption do not have better process scores, lower mortality than late adopters
DNA fingerprinting has been used to link people to crimes for decades, by matching DNA from a crime scene to DNA extracted from a suspect. Now, investigators are using other parts of the genome —such as markers for hair and eye color—to help rule people in and out as suspects. Staff Writer Gretchen Vogel talks with Sarah Crespi about whether science supports this approach and how different countries are dealing with this new type of evidence. Sarah also talks with Jill Fernandes of th e University of Queensland in Brisbane, Australia, about her Science Advances paper on a light-based technique for detecting Zi...
Probiotics are theoretically promising in primary prevention of celiac disease (CD), but research evidence on the topic is scarce. We used the data and material of a clinical double-blind randomized placebo-controlled trial on primary allergy prevention (n = 1223) to investigate in an exploratory study whether administration of a mix of pro- and prebiotics during late pregnancy and first 6 months of life was associated with prevalence of CD during 13-year follow-up. Children who fulfilled diagnostic criteria for CD (n = 11) and subjects with a serum sample available for analyzing CD antibodies (n = 867) were in...
(American College of Allergy, Asthma, and Immunology) An article published in Annals of Allergy, Asthma and Immunology shows allergies can have serious, far-reaching consequences, especially on adolescent sufferers.
Publication date: Available online 24 May 2018 Source:Journal of Environmental Chemical Engineering Author(s): Parvaze Ahmad Wani, Javid Ahmad Wani, Shazia Wahid Chromium has different oxidation states which ranges between −2 to +6. Among all these oxidation states, Cr (VI) and Cr (III) are stable but vary in biological, geochemical and toxicological properties. Cr (VI) is more toxic than Cr (III), causes allergies, irritation and respiratory disorders. When Cr (VI) is taken up by the cell, its interaction with DNA-protein complex results in the formation of DNA-DNA cross links, and thus ultimately may cause mutagen...
Bronchial thermoplasty is a treatment for asthma. It is currently unclear whether its histopathological impact is sufficiently explained by the proportion of airway wall that is exposed to temperatures necessary to affect cell survival. Airway smooth muscle and bronchial epithelial cells were exposed to media (37–70°C) for 10 s to mimic thermoplasty. In silico we developed a mathematical model of airway heat distribution post-thermoplasty. In vivo we determined airway smooth muscle mass and epithelial integrity pre- and post-thermoplasty in 14 patients with severe asthma. In vitro airway smooth muscle and ep...
Clinical&Experimental Allergy, EarlyView.
We present differences from previous US, European, and Asian guidelines and reconcile the previous differences by summarizing the 2017 revision and update published by the EAACI/GA2LEN/EDF/WAO.
Conclusions Placebo-controlled oral graded challenges to amoxicillin without prior skin testing may be safe for patients ≥ 7 years old with non-life-threatening historical reactions to penicillin. Amoxicillin can be tolerated by the majority of patients with self-reported penicillin allergy.
Publication date: Available online 23 May 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Neema Izadi, Rabinovitch Nathan
Publication date: Available online 23 May 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Julij Šelb, Urška Bidovec Stojković, Nissera Bajrović, Peter Kopač, Renato Eržen, Mihaela Zidarn, Mitja Košnik, Peter Korošec
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