CXCL12 gene silencing down-regulates metastatic potential via blockage of MAPK/PI3K/AP-1 signaling pathway in colon cancer

ConclusionThe silencing CXCL12 gene significantly inhibits the proliferation, invasion and angiogenesis ability of some types colon carcinoma cells through down-regulation of MAPK/PI3K/AP-1 signaling pathway.

http://link.springer.com/10.1007/s12094-017-1821-0

Source: Clinical and Translational Oncology - January 5, 2018 Category: Cancer & Oncology Source Type: research