Multi-step conformational transitions in heat-treated protein therapeutics can be monitored in real time with temperature-controlled electrospray ionization mass spectrometry

Analyst, 2018, Advance Article DOI: 10.1039/C7AN01655G, PaperGuanbo Wang, Pavel V. Bondarenko, Igor A. Kaltashov Sequential and small-scale conformational changes of monoclonal antibodies and antithrombin are characterized in real time in a temperature-controlled fashion. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
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