Two-years Postradiotherapy Biopsies: Lessons from MRC RT01 Trial

Conclusions Two-year postradiotherapy prostate biopsies have limited value in patients with PSA control but both positive biopsy and higher PSA status are strongly associated with future bPFS events. A policy of selected biopsy may provide an opportunity for early salvage interventions. Patient summary Routine 2-yr postradiotherapy biopsy is not recommended but can be considered in selected patients with unfavourable post-treatment prostate-specific antigen levels who are suitable for early salvage treatments. Two-year postradiotherapy biopsy results from a randomised controlled trial indicate that routine biopsy is not indicated but biopsy should be used selectively to guide local salvage treatments in patients with unfavourable post-treatment prostate-specific antigen results.
Source: European Urology - Category: Urology & Nephrology Source Type: research