An X-linked agammaglobulinemia contiguous gene syndrome with metachronous coprimary testicular cancers

This report describes an association between the X-linked agammaglobulinemia (XLA) contiguous BTK, TIMM8A, TAF7L gene syndrome and repeated testicular cancers. A previous Annals report described an association of XLA and Mohr-Tranebjaerg syndrome (MTS) in this now 28-year-old man first diagnosed at 11 months of age.1 The patient was diagnosed with XLA when he presented with acute bilateral flaccid paralysis subsequent to a varicella vaccination and was found to have hypogammaglobinemia (IgG,

Source: Annals of Allergy, Asthma and Immunology - January 4, 2018 Category: Allergy & Immunology Authors: Marcus Shaker, Ting-Jia Lorigiano, Alexandra Lucas, Sergey Devitskiy, Youdinghuan Chen, Brock Christensen Tags: Letter Source Type: research