Kisspeptin permits the sexual development of female rats with normal and precocious puberty but is not a trigger for it.

CONCLUSION: the hypothalamic KISS-1/GPR54 system might permit the onset of puberty, but is not its primary trigger. Hormone levels were lower and gonadal maturity markers in the CPP groups were worse than in the control groups.
PMID: 29298283 [PubMed - as supplied by publisher]

Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research