Updated meta-analysis of controlled observational studies: proton-pump inhibitors and risk of Clostridium difficile infection

This meta-analysis concludes that despite substantial statistical and clinical heterogeneity, the findings indicate a significant associated risk of incident CDI among PPI users, especially in general ward patients. The authors state that establishing a guideline for the use of PPI may help in the future with the control of CDI.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news