Non ‐immediate heparin and heparinoid cutaneous allergic reactions: a role for fondaparinux

Abstract Non‐immediate allergic cutaneous reactions to heparins have been increasingly reported, typically manifesting as large, eczematous plaques at sites of subcutaneous injection. Patients may demonstrate cross‐reactivity between unfractionated heparin, low molecular weight heparin and semi‐synthetic heparinoids, making finding an alternative difficult. Fondaparinux has been identified as a useful alternative in such patients; here we present the first two documented cases in Australia and a literature review.
Source: Internal Medicine Journal - Category: Internal Medicine Authors: Tags: Brief Communication Source Type: research