Silent Myocardial Infarction Linked to Heart Failure Risk

Silent and clinically manifested MI both correlated with future risk of heart failure in adjusted models
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Geriatrics, Internal Medicine, Critical Care, Emergency Medicine, Nursing, Pathology, Pulmonology, Journal, Source Type: news

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Conclusion INVESTED is the largest and longest study to assess whether high-dose influenza vaccine is superior to standard-dose influenza vaccine in reducing cardiopulmonary events in a high-risk cardiovascular population patients with heart failure and/or myocardial infarction (ClinicalTrials.gov Identifier: NCT02787044).
Source: American Heart Journal - Category: Cardiology Source Type: research
We examined the association between MI, medication changes, and post-discharge outpatient visits with 30-day readmission in 40,048 Medicare beneficiaries hospitalized for acute myocardial infarction, heart failure or pneumonia. Beneficiaries with MI were more likely to be readmitted than those without MI (14 vs. 11%). Probability of readmission was 13 and 12% when medications were dropped or added, respectively, versus 11% when no change was made. Probability of readmission also increased with outpatient visits.
Source: Administration and Policy in Mental Health and Mental Health Services Research - Category: Psychiatry Source Type: research
CONCLUSIONS: The assessment of serum IS level has prognostic utility for the management of ACS. PMID: 29780075 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
This systematic review and meta-analysis of 10 randomized clinical trials explores the role of treatment with aldosterone antagonists in patients with ST-segment elevation myocardial infarction (STEMI) without heart failure or left ventricular ejection fraction greater than 40%.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
Publication date: Available online 20 May 2018 Source:Peptides Author(s): Takeshi Tokudome, Kentaro Otani, Mikiya Miyazato, Kenji Kangawa Ghrelin, a growth hormone–releasing peptide that was first discovered in the stomach of rats in 1999, is an endogenous ligand of growth hormone secretagogue receptor. Ghrelin exerts its potent growth hormone–releasing and orexigenic activities by binding to specific receptors in the brain. Subsequent studies showed that ghrelin participates in the regulation of diverse processes, including energy balance, body weight maintenance, and glucose and fat metabolism, and demonstra...
Source: Peptides - Category: Biochemistry Source Type: research
Conclusions: Galectin-3 is directly associated with early myocardial inflammation post-MI and may represent a potential target for therapeutic inhibition. PMID: 29769800 [PubMed]
Source: Biomarker Insights - Category: General Medicine Authors: Tags: Biomark Insights Source Type: research
How much harm is done - and how quickly - by failing to maintain an exercise program? How long does it take to reverse those consequences? No-one has the final answer to those questions, firm numbers derived from the way in which the human body functions. We can look at the results of studies such as this one with some interest, however. We might compare this with studies of weight and mortality, in which the evidence suggests that lasting harm is done by carrying excess fat tissue over years, even if lost later. By analyzing reported physical activity levels over time in more than 11,000 American adults, research...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Authors: Sárközy M, Kahán Z, Csont T Abstract Small non-coding RNAs including microRNAs (miRNAs) have been recently recognized as important regulators of gene expression. MicroRNAs play myriads of roles in physiological processes as well as in the pathogenesis of a number of diseases by translational repression or mRNA destabilization of numerous target genes. The miR-106b-25 cluster is highly conserved in vertebrates and consists of three members including miR-106b, miR-93 and miR-25. MiR-106b and miR-93 share the same seed sequences; however, miR-25 has only a similar seed sequence resulting in...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Conclusions: In patients with HFrEF and multivessel CAD revascularization both with CABG and PCI resulted in similar survival rates. PCI is associated with increased risk of recurrent MI and urgent repeat revascularization, whereas the risk of stroke is similar in both methods. PMID: 29765531 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Time‑dependent and independent effects of thyroid hormone administration following myocardial infarction in rats. Mol Med Rep. 2018 May 11;: Authors: Iliopoulou I, Mourouzis I, Lambrou GI, Iliopoulou D, Koutsouris DD, Pantos C Abstract Cardiac function is reduced following myocardial infarction (MI) due to myocardial injury and alterations in the viable non‑ischemic myocardium, a process known as cardiac remodeling. The current treatments available for patients with acute MI (AMI) reduce infarct size, preserve left ventricular (LV) function and improve survival; however, these treatments do no...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
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