Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma

Conditions:   Allergic Asthma;   Airway Remodelling;   Extracellular Matrix Alteration Interventions:   Procedure: Bronchial challenge with allergen;   Other: Co-culture formation;   Other: Inhibition of Wnt and Smad signaling pathways;   Other: Extracellular matrix turnover and deposition assessment;   Biological: Dermatophagoides pteronyssinus allergen;   Device: Dosimeter ProvoX ( Ganshorn);   Biological: Eosinophils;   Biological: Airway smooth muscle cells;   Biological: Fibroblasts Sponsors:   Lithuanian University of Health Sciences;   Research Council of Lithuania;   University of Groningen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials