Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma
Conditions: Allergic Asthma; Airway Remodelling; Extracellular Matrix Alteration Interventions: Procedure: Bronchial challenge with allergen; Other: Co-culture formation; Other: Inhibition of Wnt and Smad signaling pathways; Other: Extracellular matrix turnover and deposition assessment; Biological: Dermatophagoides pteronyssinus allergen; Device: Dosimeter ProvoX ( Ganshorn); Biological: Eosinophils; Biological: Airway smooth muscle cells; Biological: Fibroblasts Sponsors: Lithuanian University of Health Sciences; Research Council of Lithuania; University of Groningen Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials